Experts discuss the fundamentals of wireless, long-term EEG recording in small animals and present new research capabilities enabled through the integration of technology and physiological analysis systems.
Recording and analyzing multi-channel electroencephalogram (EEG) signals in small animals offers detailed insights into brain activity, an important process to many research applications including psychophysiology, stroke, motor disorder, sleep, circadian rhythms, seizures and epilepsy, to name a few. However, traditional methods of obtaining long-term EEG data provide a myriad of challenges, including surgical complexity, an inability to utilize additional transmitters and limitations when trying to study small, neonatal rodents. Moreover, attempting to co-register multi-channel EEG with complimentary physiological measurements adds another level of complexity, requiring the integration of multiple systems. If this is done incorrectly it can lead to data acquisition error, poor measurement synchronization and ultimately misleading results.
In this webinar sponsored by BIOPAC Systems and Epitel, Frazer Findlay and Mark Lehmkuhle discuss study design and demonstrate correct equipment set up and operation when recording small animal EEG. Specifically, Mr. Lehmkuhle demonstrates the application of the implantable Epoch wireless EEG/neural signal system — he reviews surgical procedure and transmitter implantation, device setup, and best-practices that will lead to successful and reproducible data collection.
Following, Mr. Findlay provides a detailed demonstration in BIOPAC AcqKnowledge software, including how to set up multi-channel data acquisition, integrate video capture, interrogate EEG data and improve signal quality, complete EEG frequency analysis, and how to use important software functions (such as “Focus Areas”) for seizure detection and sleep analysis.
To access the webinar recording, please click the button and complete the registration form — once authorized the video will load in a separate viewing window.
- 00:00 – 01:17: Introduction
- 01:20 – 19:41: Surgical Preparation & Epoch Transmitter Implantation
- 19:43 – 23:58: Setting Up The Epoch Biopotential Recording System with BIOPAC MP150/160 Acquisition Systems
- 24:00 – 49:00: AcqKnowledge Software Demonstration (EEG analysis functions)
- 49:02 – 59:14: Q&A Session
To download a PDF copy of the presentation, click on the “LinkedIn SlideShare” icon located in the bottom-right corner of the slide-viewer. From the SlideShare landing page click the “Download” button to retrieve the file.
Mark Lehmkuhle, PhD
BIOPAC Systems Inc.