Exploring Predictive Biomarkers and ERK1/2 Phosphorylation: A New Horizon in Forecasting Survival and Response to Immune Checkpoint Blockade in Glioblastoma Treatment
In this webinar, Victor Arrieta highlights the link between p-ERK activation and improved survival in rGBM patients using anti-PD-1 immunotherapy.
Spatial Phenotyping: A Revolutionary Approach to Biomarker Discovery for Cancer Immunotherapy
Dr. Arutha Kulasinghe discusses the potential of single-cell spatial phenotyping in biomarker analysis and how it can be used to characterize tumor microenvironments.
Longitudinal Plasma Samples: Paving the Way for Precision Oncology
Experts present a cell-free plasma biobank and describe the role of longitudinal plasma samples for cancer research, disease monitoring, and biomarker development.
Biomarker Imaging for Preclinical Cancer Research
Cancer biomarkers that do not cross the translational gap to clinical practice can still further research and drug discovery. In this article, we review several techniques commonly used for cancer biomarker imaging at preclinical stages, as well as recent technological advances.
Extracellular Vesicles as Breast Cancer Biomarkers
Triple-negative breast cancer is particularly aggressive, challenging to treat, and accounts for 15-20% of all breast cancers. In this blog, we review a study published in Nature Communications that examines the transforming growth factor-β targetable signaling pathway, its role in malignant cancer progression and immune suppression, and tumor-derived extracellular vesicles as diagnostic and prognostic biomarkers.
Cutting Edge Conversations: Biomarkers – Challenges and Opportunities
The 5th and final episode in the Cutting Edge Conversation series for 2021 features Dr. Morad Nakhleh, Natalie Smith, and Dr. Bhavika Patel as they discuss industry challenges and innovations surrounding biomarkers in life science research and precision medicine
Translational Applications of MiniPDX: An In Vivo Organoid Assay in New Drug R&D
Join Dr. Danyi Wen as she describes a novel drug efficacy test using Patient Derived Xenograft (PDX) samples to measure drug efficacy and identify therapeutic candidates in personalized oncology treatments.
Plasma Proteomics: The Next Frontier of Biomarker Discovery in the Precision Medicine Era
Plasma proteomics is increasingly recognized as a fundamental approach to accelerate biomarker discovery and drug development, taking precision medicine to the next level.
