How to Create CRISPR-Edited T Cells More Efficiently for Tomorrow’s Cell Therapies
Steven Loo-Yong-Kee presents Artisan Bio's STAR-CRISPR system for optimized gene editing in cell therapy, with a focus on the genetifc modification of T cells for cancer immunotherapy.
Protocol Preview: Creating an Artificial Human Thymus in Mice
The majority of treatments for immunodeficiencies are temporary fixes, in part due to a lack of preclinical models that can accurately predict immune responses in humans. However, a novel model recently published in Nature Methods has potential to greatly improve future immune response studies, which we review in this blog post.
#ExpertAnswers: Marcela Maus on Inflammation and Immunophysiology
Dr. Marcela Maus discusses the components and technologies used in making a T cell product, important considerations for efficacy, and underlying mechanisms of toxicity and resistance.
Engineered T Cells for Cancer
Dr. Marcela Maus discusses CAR T Cell research, the components and technologies used in making a T cell product, important considerations for efficacy, and underlying mechanisms of toxicity and resistance.
