#ExpertAnswers: Jiahui Yang on Antibody Discovery Platforms
Dr. Jiahui Yang provides an overview of antibody discovery platforms and discusses how single B cell sorting can be used to generate functional monoclonal antibodies for a range of applications including disease diagnosis and therapeutics.
#ExpertAnswers: Luke Holloway on Protein Characterization
Luke Holloway reviews light scattering-based methods for protein characterization and explains their utility in understanding aggregation propensity of monoclonal antibodies.
#ExpertAnswers: Joanna Hummer and Florie Le Prieult on cOFM for in vivo Cerebral Fluid Sampling
Experts discuss cerebral open flow microperfusions use, and honing in specifically on its use in drug development and neurodegenerative disease.
#ExpertAnswers: Merry Lindsey on Aging Science
Join Merry Lindsey, PhD as she answers questions from a recent webinar that focuses on her research involving the physiology of recovery from cardiac events.
#ExpertAnswers: Yasaman Soudagar and Roshni Christo on Neuronal Calcium Imaging
Dr. Yasaman Soudagar and Dr. Christo from Neurescence answer questions from a recent webinar where they discuss how to use calcium imaging
#ExpertAnswers: Mariana Kaplan on Inflammation and Immunophysiology
Mariana Kaplan highlights the role of systemic autoimmunity in the development of vasculopathy and atherosclerosis and discussing potential strategies to prevent these complications.
#ExpertAnswers: Satish Raj and Nasia Sheikh on Initial Orthostatic Hypotension
Dr. Satish Raj and Nasia Sheikh discuss new research findings on the hemodynamic mechanisms underlying initial orthostatic hypotension.
#ExpertAnswers: Jonas Treebak and Alexander Bartelt on Metabolic Adaptations
In this episode of #ExpertAnswers join Dr. Jonas Treebak and Dr. Alexander Bartelt as they answer questions from a recent [...]
#ExpertAnswers: Sue Bodine on Aging Science
Join Sue Bodine, PhD as she answers questions from a recent webinar that focuses on the decline in muscle mass with aging and the role that innervation plays in muscle atrophy.
#ExpertAnswers: Paul Marvar on Fear and Cardiovascular Disease
Dr. Paul Marvar discusses research pairing behavioral and cardiovascular responses to cued fear learning and demonstrate how fear-based disorders can contribute to cardiovascular disease risk.
#ExpertAnswers: Stefano Gaburro and Brun Ulfhake on Aging Science
Join Stefano Gaburro and Brun Ulfhake as they present methods of caged rodent monitoring and better animal welfare that will lead to improved studies of neurodegenerative disease models.
#ExpertAnswers: Xuebin Qin on Inflammation and Immunophysiology
Dr. Xuebin Qin talks about his lab’s development and characterization of new models of SARS-CoV-2 and HIV, and how they use these models to study cardiovascular injury associated with infection.
#ExpertAnswers: Aileen King on Experimental Protocol
Dr. Aileen King discusses how even small changes to experimental protocol can substantially impact both welfare and data interpretation when studying blood glucose homeostasis in mice.
#ExpertAnswers: Anna Cavaccini & James Dooley on Sensorimotor Network Development
Experts share insights into the development of rodent sensorimotor neuronal circuits during early postnatal life in wakefulness and REM sleep.
#ExpertAnswers: Edward Bahnson on Light-sheet Fluorescence Microscopy and Vascular Injury
Edward Bahnson, PhD presents the development and validation of a methodological approach using light-sheet fluorescence microscopy (LSFM) for the imaging of preclinical models of vascular injury with a focus of minimizing analysis bias while increasing precision and reproducibility.
#ExpertAnswers: Rohan Jagirdar on Sleep and Alzheimer’s Disease
In this episode of #ExpertAnswers join Rohan Jagirdar, PhD, from Baylor College of Medicine, as he answers questions from a [...]
#ExpertAnswers: Fiona Harrison on Early Alzheimer’s Disease
Dr. Fiona Harrison, discusses how vitamin C deficiency and exposure to toxins can impact glutamate uptake and clearance, and how even small changes in neural signaling can be detected by monitoring EEG activity and correlated with performance in learning and memory tasks.
#ExpertAnswers: Weixi Liu on Extractables and Leachables Analysis
Dr. Weixi Liu offers a strategy for extractables and leachables analysis using a multidetector strategy with LC-MS, GC-MS, ultraviolet and charged aerosol detection and flame ionization detection.
#ExpertAnswers: Suzanne De La Monte on Aging Science
In this episode of #ExpertAnswers join Suzanne de la Monte, MD, MPH, from Brown University, as she answers questions from [...]
#ExpertAnswers: Alexandra Lubin & Jason Otterstrom on Automated Microscopy
Experts discuss the use of deep learning-powered automated microscopy and image analysis for fast, in vivo zebrafish screening.
#ExpertAnswers: P Boon Lim and Melanie Dani on Autonomic Dysfunction in Long-COVID
Experts from Imperial College Healthcare NHS Trust describe the presenting symptoms and diagnostic challenges for patients in their syncope clinic presenting with autonomic dysfunction in Long-COVID.
#ExpertAnswers: Dudley Lamming on Aging Science
Join Dudley Lamming, PhD an Associate Professor at the University of Wisconsin-Madison, as he answers questions from a recent webinar that focuses on his research involving how diets can affect metabolic health and longevity.
#ExpertAnswers: Phil Griffiths on Telemetry
Join Phil Griffiths, PhD as he answers questions from a recent webinar on Telemetry 101 where he discusses the benefits of using telemetry and the specific advantages of ADInstruments’ new small animal telemetry systems.
#ExpertAnswers: Marcela Maus on Inflammation and Immunophysiology
Dr. Marcela Maus discusses the components and technologies used in making a T cell product, important considerations for efficacy, and underlying mechanisms of toxicity and resistance.
#ExpertAnswers: Caroline Williams and Eric Riddell on Ecophysiology and Climate Change
Caroline Williams, PhD and Eric Riddell, PhD answer questions from a recent webinar where they discuss their research involving climate change and the ecophysiological effects of changing global temperatures on organismal biology and survival.