Leveraging Programmable CRISPR-Associated Transposases for Next-Generation Genome Engineering
Dr. Sam Sternberg discusses a novel CRISPR-Cas9 system using programmable, RNA-guided transposase, and highlights its implications for kilobase-scale genome engineering in cell and gene therapies.
Developing Retinal Gene Therapy for Zellweger Spectrum Disorder (ZSD)
Catherine Argyriou, PhD, discusses peroxisome disease and the development of a retinal gene therapy for PEX1-mediated Zellweger Spectrum Disorder.
Real-time IntraVital Microscopy (IVM): In Vivo Cellular-level Imaging of Internal Organs in a Live Animal
Join Pilhan Kim, PhD for an in-depth discussion on the All-in-One intravital two-photon and confocal microscopy system.
Protocol Preview: In Vivo Gene Therapy Using Peptide-Based Delivery
Although gene therapy has been in discussion for decades, its translation to clinical practice has been a slow and challenging process. As a solution to this translational challenge, Allen et al. have proposed a peptide-based delivery method of Cre recombinase for in vivo gene therapy, which we review in this blog post.
#ExpertAnswers: Ejvind Mørtz on Protein AnalysisDarius Soo Lum
Ejvind Mørtz discusses the benefits and applications of mass spectrometry (MS)-based host cell protein (HCP) analysis and why HCP ELISAs are insufficient for documenting product-related impurities.
Rethink your Impurity Analysis Strategy
In this webinar, Dr. Ejvind Mørtz discusses the benefits and applications of mass spectrometry (MS)-based host cell protein (HCP) analysis and why HCP ELISAs are insufficient for documenting product-related impurities. Watch to learn where to apply the assay in a typical process and what you gain from deploying it to your workflow.
Cutting Edge Conversations: Discovering New Innovations in Oncology
Experts discuss progress in cancer research, including novel treatments, experimental therapies, and drug development.
How Transformative Antibody Technology Can Improve Your Bioanalytical Assays
Dr. Royle discusses how the combination of antibody phage display and SpyTag technologies can generate critical antibody reagents with a difference.
Restoring Vision – Optogenetic Gene Therapy Targeted at Human ON-Bipolar Cells
Dr. Hulliger discusses his work with a new promoter that is raising hopes of improving the quality of life for people suffering from blindness.