Molecular Signals Mediating Increases in Muscle Size and Function
In this webinar, Dr. Bert Blaauw elucidates skeletal muscle regulatory pathways and offers approaches to tackle muscle deficits for therapy.
Cut and Paste of Myosin Binding Protein-C in Striated Muscles
Dr. Samantha Harris discusses the development of three new mouse models in her lab, engineered to target and replace specific myosin binding protein-C paralogs in muscle fibers and impact of their mutations on skeletal and cardiac muscle diseases.
#ExpertAnswers: Sarah Greising on Muscle Injury Recovery
Sarah Greising discusses the current pathophysiologic understanding of the skeletal muscle remaining following traumatic musculoskeletal injuries.
Functional Recovery of the Musculoskeletal System Following Injury – Leveraging the Large Animal Model
Watch Dr. Sarah Greising discuss the current pathophysiologic understanding of the skeletal muscle remaining following traumatic musculoskeletal injuries.
#ExpertAnswers: Charlotte Peterson & Jack Guralnik on Aging Science
In this episode of Expert Answers, Dr. Jack Guralnik and Dr. Charlotte Peterson answer questions about sarcopenia, the physiological mechanisms underlying the disease, and the current avenues of treatment and assessment.
The Challenges of Sarcopenia: Definition, Underlying Mechanisms, Interventions, and Outcomes
Dr. Charlotte Peterson and Dr. Jack Guralnik will discuss the challenges of sarcopenia. They will define the disease and provide an in depth overview of the underlying mechanisms of pathology. They will then share some potential therapeutic interventions and disease outcomes for patients.
Science of Aging: A Physiological & Translational Perspective
Science of Aging - A Physiological & Translational Perspective: A webinar series covering fundamentals, late-breaking research and novel discoveries in the field of aging science.
ASO-Mediated DNM2 Knockdown for Centronuclear Myopathies
Suzie Buono discusses the work she and her team have done to provide an example of treating a dominant disease by targeting both alleles, suggesting that this strategy may be applied to other dominant diseases.
#ExpertAnswers: Tim West & Matt Borkowski on Single Muscle Fiber Mechanics
In this episode of Expert Answers join Dr. Tim West and Matt Borkowski for a discussion on how to properly isolate and prepare, and assess muscle performance and contractile function in single muscle fibers.
How to Plan and Execute Contractile Measurements in Permeabilized Muscle Fibers
Experts discuss the A-to-Z of assessing muscle performance and contractile function in single muscle fibers.
The MRL/MpJ Mouse Strain Is Not Protected From Muscle Atrophy And Weakness After Rotator Cuff Tear
The MRL/MpJ mouse strain has been touted as a "superhealer" although different tissues have previously displayed different levels of healing ability. We sought to test that ability in skeletal muscle.
