Protocol Preview: In Vivo Gene Therapy Using Peptide-Based Delivery
Although gene therapy has been in discussion for decades, its translation to clinical practice has been a slow and challenging process. As a solution to this translational challenge, Allen et al. have proposed a peptide-based delivery method of Cre recombinase for in vivo gene therapy, which we review in this blog post.
#ExpertAnswers: Joanna Hummer and Florie Le Prieult on cOFM for in vivo Cerebral Fluid SamplingShiv Nair
Experts discuss cerebral open flow microperfusions use, and honing in specifically on its use in drug development and neurodegenerative disease.
Cerebral Open Flow Microperfusion (cOFM) for in vivo Cerebral Fluid Sampling – Comparison of cOFM and Microdialysis
Dr. Joanna Hummer and Dr. Florie Le Prieult share insights into cOFM's use and utility in the broader neuroscience field and specifically for the development of drugs for neurodegenerative diseases.
#ExpertAnswers: Robert Doyle on Novel Drug Delivery MethodsDarius Soo Lum
Robert Doyle discusses novel drug delivery methods for basic research, drug discovery and development.
#ExpertAnswers: Christian Schnell on Drug Delivery MethodsDarius Soo Lum
Christian Schnell discusses novel drug delivery methods for basic research and novel infusion technologies.