Novel Targets for Alzheimer’s Disease Treatment: Medin and PLD3
Given that Alzheimer's disease is multifactorial and heterogenous, drug development progress is more likely to occur if multiple pathways are considered. Two recent Nature publications have potentially identified medin and PLD3 as new targets for Alzheimer’s disease treatment, which we summarize in this mini-review.
#ExpertAnswers: Dudley Lamming on the Influence of Sex and Genetic Background on DietDarius Soo Lum
Dudley Lamming, PhD, explains that “We Are More Than What We Eat”; Sex and Genetic background are important factors in observing responses to diet in mice.
Industry Insights with Chris Rand from Aurora ScientificDarius Soo Lum
Chris Rand delves into the start and evolution of Aurora Scientific, and their journey within the preclinical research world.
We Are More Than What We Eat: Dietary Interventions Depend on Sex and Genetic Background
Dudley Lamming, PhD, explains how sex and strain type are highly important factors in observing responses to dietary interventions in mice.
Talking Real Science with Chris PerryDarius Soo Lum
Chris Perry shares his career path and recent project of creating a CRO to bring more opportunity to deliver solutions for muscle disorders while still benefiting his trainees.
European Council for Cardiovascular ResearchSarah McFarlane
The history of the European Council for Cardiovascular Research (ECCR) goes back more than 30 years when the ‘European Blood Pressure Group’ held its [...]
#ExpertAnswers: Andrea Bonetto on the Musculoskeletal Complications of Cancer and its TreatmentsDarius Soo Lum
Andrea Bonetto, PhD, answers questions from his recent webinar on how bone preservation directly impacts muscle size and function in cachexia, and contributes to new treatments for cancer.
Translational Science Panel: Research Insights and Best Practice for Clinical Relevance
Join Aaron Phillips, Fiona McBryde, and Kevin O'Gallagher for a 1-hour Translational Science panel.
Translational Applications of MiniPDX: An In Vivo Organoid Assay in New Drug R&D
Join Dr. Danyi Wen as she describes a novel drug efficacy test using Patient Derived Xenograft (PDX) samples to measure drug efficacy and identify therapeutic candidates in personalized oncology treatments.
Musculoskeletal Complications of Cancer and its Treatments
Dr. Andrea Bonetto discusses the importance of musculoskeletal preservation in cancer treatment and shares evidence that bone preservation directly impacts muscle size and function in cachexia.
Minipigs Research Forum Announces 12th Annual Meeting in Barcelona
Minipigs Research Forum announces 12th annual meeting in Barcelona with focuses on analytical methods and biomarkers, imaging and devices, species selection, and disease models.