Developing a Novel Gene Therapy for Kcnv2 Retinopathy
Livia Carvalho, PhD discusses her team's successful development of a novel AAV-based gene therapy approach for KCNV2 retinopathy in a Kv8.2 knockout mouse model.
Symposium: Opportunities, Hopes, and Challenges in Translating Visual Restoration from Mouse to Human
Striatech celebrates its 5th anniversary with a top-class Symposium on the topic of translating visual restoration from mouse to human.
Postsynaptic Neuronal Activity Promotes Retinal Axon Regeneration
Supraja’s presentation provides insights into mechanisms that promote retinal ganglion cell (RGC) axon regeneration in vertebrates.
Assessing Neuroinflammation-Related Neural Damage by Monitoring the Retinotectal System
Dr. Janos Groh discusses how neuroinflammation amplifies neural damage and disease outcome in models of various disorders, and the value of monitoring the retinotectal system to assess neural disease progression and associated treatment efficacy.
The Role of Nogo-A in Visual Deficits Induced by Retinal Injury
Julius Baya Mdzomba, PhD shows the link between Nogo-A, a membrane protein and potent inhibitor of neuronal growth, and visual deficits aggravation after retinal injury.
Visual Acuity as a Relevant Phenotype in Mouse Models of Rare Disease
Zoë Bichler, PhD and Maximiliano Presa, PhD present various projects where visual acuity measurements have been valuable for characterizing progression in rare diseases.
