The Use of Vascular Access Buttons in Rabbits for PK/TK Studies
Jon Ehrmann presents the use of vascular access buttons in rabbits as a solution to challenges in venipuncture, enhancing blood collection, and intravenous administration for pharmacokinetic studies.
Evaluation of TruVivo, an All-Human Hepatocyte Model for Mechanistic DMPK Investigations
Join Diane Ramsden, PhD, and Lindsey Whaley, MS, for an inside look at TruVivo™, a novel all-human in vitro hepatocyte system developed by LifeNet Health LifeSciences.
Video Interview – ALZET Osmotic Pumps
Clarisa Peer discusses ALZET Osmotic Pumps, the gold standard for controlled, automatic dosing of compounds in various research areas, including neuroscience, cancer research, cardiovascular, endocrinology, pharmacology research, and more.
#ExpertAnswers: Ejvind Mørtz on Protein Analysis
Ejvind Mørtz discusses the benefits and applications of mass spectrometry (MS)-based host cell protein (HCP) analysis and why HCP ELISAs are insufficient for documenting product-related impurities.
Rethink your Impurity Analysis Strategy
In this webinar, Dr. Ejvind Mørtz discusses the benefits and applications of mass spectrometry (MS)-based host cell protein (HCP) analysis and why HCP ELISAs are insufficient for documenting product-related impurities. Watch to learn where to apply the assay in a typical process and what you gain from deploying it to your workflow.
#ExpertAnswers: Edward LeCluyse and Paul Gallant on a Novel Hepatic Triculture System
Edward LeCluyse and Paul Gallant discuss their novel all-human hepatic triculture system including its benefits and applications.
Understanding Health Care Decision Maker Preferences for Optimized Engagement
Hear market research and payer experts explain the best practices and preferences of healthcare decision-makers.
A Novel, All-Human Hepatic Triculture System
Join Edward LeCluyse and Paul Gallant as they offer insight into a novel, all-human hepatic triculture and how this unique system addresses the need for a convenient and human-relevant long-term hepatic culture.
Optimizing Real-World Evidence for Maternal and Neonatal Outcomes
Experts from health system innovators (C-Path), patients (PreemieWorld), healthcare payers (HealthCore/Anthem), and industry (Bayer) provide insights into improving neonatal outcomes using RWE.
Translational Applications of MiniPDX: An In Vivo Organoid Assay in New Drug R&D
Join Dr. Danyi Wen as she describes a novel drug efficacy test using Patient Derived Xenograft (PDX) samples to measure drug efficacy and identify therapeutic candidates in personalized oncology treatments.
Academy of Surgical Research Virtual Annual Meeting 2021
Register to watch the on-demand 37th Academy of Surgical Research Virtual Meeting, a three-day exploration of surgical techniques, innovative research, and technology advancements.
#ExpertAnswers: Christian Schnell on Pharmacology Studies in Oncology Research
Christian Schnell, Associate Director of Oncology at Novartis in Basel, answers questions on PK-PD assessment and corresponding antitumor activity in pharmacology studies for oncology research.
Compound Delivery, PK-PD, & Validation Studies in Oncology Research
Dr. Christian Schnell describes his work involving implantable infusion pump studies in rodents and the advancement of pharmacological interventions in oncology research.
#ExpertAnswers: Chris Ward, Ramzi Khairallah & Sharon Hesterlee on Muscular Dystrophy
This episode of #ExpertAnswers features Dr. Chris Ward, Co-founder and scientific officer at myologica, Dr. Ramzi Khairallah, co-founder and president [...]
Academy of Surgical Research Virtual Annual Meeting 2020
Register for the 36th Annual Academy of Surgical Research Virtual Meeting to join surgical research professionals around the world in a two-day exploration of surgical techniques, research applications, technology advancements and industry trends.
Considerations for Rigorous Pre-clinical Studies in Murine Muscular Dystrophy
Experts present key considerations in the design of rigorous preclinical studies in rodent models of muscular dystrophy, including animal model selection, assays and endpoints, and how your results can inform translation to the clinic.
#ExpertAnswers: Miroslaw Janowski and Piotr Walczak on Imaging for Precision Medicine
Miroslaw Janowski and Piotr Walczak discuss how PET/CT imaging can be used to enable image-guided neurointerventions and to study targeted delivery and clearance of therapeutic agents.
A New Frontier of Precision Medicine: Using PET for Image-Guided Neurointerventions
Experts discuss how PET/CT imaging can be used to enable image-guided neurointerventions and to study targeted delivery and clearance of therapeutic agents.
Identifying Preclinical Immunotherapy Candidates Using a NHP Exploratory Toxicology Platform
Dr. Thomas Scullion discusses how to leverage NHP exploratory toxicology studies to guide and explore lead optimization, dosing paradigms, and future GLP studies.
#ExpertAnswers: Robert Gould and Michael Girand on Utilizing EEG to Study Sleep, Substance Use and CNS Disorders
Robert Gould and Michael Girand discuss methods and applications for the use of EEG as a biomarker for sleep, substance use disorder and CNS disorders.
#ExpertAnswers: John Cirrito & Candace Rhode-Johnson on Micro-dialysis and Neuroscience
In this episode of Expert Answers, John Cirrito and Candace Rhode-Johnson discuss the use of a novel movement responsive rodent caging system.
Turn Away from Traditional Tethering and Towards a Better Method for Data Collection
Experts discuss the use of a novel movement responsive rodent caging system as a means to minimize animal stress and enable unique discovery in many research applications, namely neuroscience, animal behaviour, drug discovery and cardiometabolic disease.
Harnessing EEG Methods to Improve Basic and Translational Research for CNS Disorders
Dr. Robert Gould and Mike Girand discuss methods and applications for the use of EEG as a highly translational biomarker for sleep, substance use disorder and CNS disorders.
#ExpertAnswers: Melanie White on Isolated Langendorff Heart Principles
Melanie White discusses basic isolated Langendorff heart principles, key experimental design considerations, core technology requirements and best practice tips to support consistency and validation of your research.
Reversing Hypertriglyceridemia and Hepatic Steatosis in Dysmetabolic NHPs with a Controlled-Release Mitochondrial Protonophore (CRMP)
Leigh Goedeke, PhD reviews spontaneous nonhuman primate (NHP) models of NAFLD and metabolic syndrome as a more clinically-relevant preclinical study platform.