Industry Insights with Crown Bioscience: Targeting T Cells Within the Cancer Immunity Cycle
Saskia De Man, Marrit Putker, and Pirouz Daftarian from Crown Bioscience discuss the impact of T cell-directed immunotherapy on the cancer-immunity cycle.
#ExpertAnswers: Marrit Putker, Saskia De Man, and Pirouz Daftarian on T Cell-Directed Immunotherapy
Marrit Putker, Saskia De Man, and Pirouz Daftarian from Crown Bioscience discuss T cell-directed immunotherapy on the cancer-immunity cycle, including mechanisms and targets capable of modulating and enhancing T cell activity and the application of methods and models including organoids and high content imaging.
Orphan Receptor GPR55: A New Therapeutic Target for Atherosclerosis?
Since the role of GPR55 in adaptive B cell response regulation has not yet been reported in the context of atherosclerosis, Guillamat-Prats et al. have investigated how GPR55 in B cells affects atherosclerosis development. In this blog post, we highlight the main findings from this study, which was published this month in Nature Cardiovascular Research.
Protocol Preview: Creating an Artificial Human Thymus in Mice
The majority of treatments for immunodeficiencies are temporary fixes, in part due to a lack of preclinical models that can accurately predict immune responses in humans. However, a novel model recently published in Nature Methods has potential to greatly improve future immune response studies, which we review in this blog post.
Targeting T Cells Within the Cancer Immunity Cycle
In this webinar, speakers will discuss the role of T cell biology in cancer immunotherapy.
The Cancer-Immunity Cycle: Research Solutions for Preclinical Immuno-Oncology
Cancer immunotherapy has undoubtedly expanded the cancer treatment landscape and improved patient outlook, which can in part be attributed to the recognition of the importance of the cancer-immunity cycle as a whole. In this blog, we provide an overview of the cancer-immunity cycle and highlight some preclinical models that can facilitate cancer immunotherapy research.