APS Physiology in Disease Modeling and Drug Development Roundtable
Key opinion leaders in cardiovascular physiology and bioengineering discuss best practices and challenges when modeling cardiomyopathies and other cardiovascular diseases using stem cells, engineered tissues and other novel platforms.
Skin-on-Chip for Preclinical Herpes Disease Modeling
Organs-on-a-chip are attractive alternatives for bridging the translational gap between preclinical and clinical stages in vaccine development, particularly for herpes simplex virus (HSV). In this blog post, we review an article from Nature Communications on a skin-on-chip device for modeling HSV infection, as well as evaluating immune responses and antiviral drug efficacy (featured image © 2022 Sun et al., licensed under CC BY 4.0).
Talking Real Science with Aaron Phillips
Dr. Aaron Phillips combines integrated physiology and neuroscience to understand hemodynamic instability and spinal cord injury in pre-clinical and clinical models.
#ExpertAnswers: Raul Andero on Fear Memory in a Rodent Model
Raul Andero answers questions from a webinar where he presented research on sex-dependent differences in the consolidation of fear memory in a rodent model.
#ExpertAnswers: Emma Karey on E-Cigarettes and Health Risks
Emma Karey challenges the convention that extant cigarette endpoints sufficiently capture the health risks of vaping.
European Council for Cardiovascular Research
The history of the European Council for Cardiovascular Research (ECCR) goes back more than 30 years when the ‘European Blood Pressure Group’ held its [...]
Sex Differences in Fear Memory
Dr. Raül Andero Galí presents research on sex-dependent differences in the consolidation of fear memory in a rodent model.
Assessing Toxicity and Health Risks of E-cigarettes: How to Take Aim at a Moving Target
Dr. Emma Karey presents research that challenges the convention that extant cigarette endpoints sufficiently capture the health risks of vaping, and provides a translational framework for how to integrate scientific principles and novel conditions.
#ExpertAnswers: Dale Abel on Aging Science
Dale Abel answers questions from a recent webinar that focuses on the mechanisms underlying heart failure in aging and diabetes.
Translational Science Panel: Research Insights and Best Practice for Clinical Relevance
Join Aaron Phillips, Fiona McBryde, and Kevin O'Gallagher for a 1-hour Translational Science panel.
Translational Applications of MiniPDX: An In Vivo Organoid Assay in New Drug R&D
Join Dr. Danyi Wen as she describes a novel drug efficacy test using Patient Derived Xenograft (PDX) samples to measure drug efficacy and identify therapeutic candidates in personalized oncology treatments.
Plasma Proteomics: The Next Frontier of Biomarker Discovery in the Precision Medicine Era
Plasma proteomics is increasingly recognized as a fundamental approach to accelerate biomarker discovery and drug development, taking precision medicine to the next level.
Bruker Micro-CT/XRM User Meeting
A two-day virtual user meeting showcasing state-of-the-art applications in both life and material sciences, and provides the latest Bruker news about hardware and software.
Cardiac Glucose Metabolism: Heart Failure in Diabetes and Aging
Join Dr. Dale Abel for a deep dive into the mechanisms underlying heart failure in aging and diabetes.
#ExpertAnswers: Dudley Lamming on Aging Science
Join Dudley Lamming, PhD an Associate Professor at the University of Wisconsin-Madison, as he answers questions from a recent webinar that focuses on his research involving how diets can affect metabolic health and longevity.
Quality, Quantity and Timing: Regulating Healthspan and Lifespan With Diet
Join Dudley Lamming, PhD for a deep dive into his research involving how diets can affect metabolic health and longevity.
#ExpertAnswers: Lais Berro on the Behavioral Effects of Benzodiazepines
Dr. Lais Berro discusses her research demonstrating the anxiolytic, sedative and abuse-related effects of benzodiazepine drugs in rhesus monkeys.
Bruker @ ISMRM 2021
Full-day scientific workshop celebrating advancements and innovation in preclinical neuroscience and metabolic research.
#ExpertAnswers: Brendan Dougherty on Sex Hormones and Neuroplasticity
Dr. Brendan Dougherty discusses respiratory neuroplasticity, and how sex hormones affect the regulation of breathing.
PET/MRI Occupancy Studies – Basic Principles and Applications in Neuroimaging
Join PET experts Dr. Placzek and Dr. Mandeville for an overview of their current projects centring around the core principles of PET and MRI occupancy studies.
Using EEG to Evaluate the Behavioral Effects of Benzodiazepines in Rhesus Monkeys
Lais Berro, PhD presents recent research demonstrating the anxiolytic, sedative and abuse-related effects of benzodiazepine drugs, and how they correlate with telemetry-based EEG recordings in a translational non-human primate model.
How Estrogen Influences Respiratory Function and Spinal Respiratory Neuroplasticity
Dr. Brendan Dougherty discusses how sex hormones influence respiratory function and the development of respiratory neuroplasticity.
