Talking Real Science with Jared Oenick
Jared Oenick gives us a brief look at what his inspiration for science is, as well as where he plans to take his career in the future. He recounts how having a personalized experience with renal disease not only encouraged him, but gave him the clarity needed to find solutions to the problems facing many patients today.
Talking Real Science with Martin Young
Martin Young shares his career path, background, and the influence and guidance he has received from through generations of scientific mentorship.
#ExpertAnswers: Davide Boido and Antoine Bergel on Multimodal Neuroimaging
Davide Boido and Antoine Bergel discuss their work on how state-of-the-art multimodal neuroimaging can be coupled with functional ultrasound to study neurovascular coupling across vigilance states.
#ExpertAnswers: Jastyn Pöpplau and Marilena Hnida on Prefrontal Networks
Jastyn A. Pöpplau and Marilena Hnida discuss their research on prefrontal networks in developing head-fixed mice, and the role of these networks in cognition and models of neurodevelopmental diseases.
#ExpertAnswers: Artur Federowoski on Cardiovascular Dysautonomia in Post-COVID-19
Artur Federowski explains CV dysautonomia as a specific sequalae of acute COVID-19 and guides the audience in the diagnostic work-up of PASC patients with suspected cardiovascular complications.
Industry Insights with Crown Bioscience: Analyzing the Suppressive TME in In Vitro Based Assays
Nataliia Beztsinna and Marten Hornsveld from Crown Bioscience talk about native and reconstituted TME assays, how they can help in the preparation for clinical trials, and what kinds of therapies in development would benefit the most from this kind of testing.
Talking Real Science with Yelena Akelina
This episode of #ShareScience features Yelena Akelina, DVM, MS, a Research Scientist and the Co-Director/Instructor in Clinical Microsurgery at the Microsurgery Research and Training Lab at Columbia University.
#ExpertAnswers: Connar Westgate on Intracranial Pressure Measurements
Connar Westgate discusses his research involving intracranial pressure measurements and the importance of understanding this physiological parameter for maintaining normal central nervous system function.
#ExpertAnswers: Audrey Dubourg and Gareth Guenigault on the Organ-On-A-Chip Approach
Audrey Dubourg and Gareth Guenigault from CN Bio discuss the value that an organ-on-a-chip approach can bring to drug discovery and development workflows, and how the regulatory landscape is shifting to encourage their widespread adoption.
#ExpertAnswers: Sarah Greising on Muscle Injury Recovery
Sarah Greising discusses the current pathophysiologic understanding of the skeletal muscle remaining following traumatic musculoskeletal injuries.
Industry Insights with Crown Bioscience: Targeting T Cells Within the Cancer Immunity Cycle
Saskia De Man, Marrit Putker, and Pirouz Daftarian from Crown Bioscience discuss the impact of T cell-directed immunotherapy on the cancer-immunity cycle.
#ExpertAnswers: Marrit Putker, Saskia De Man, and Pirouz Daftarian on T Cell-Directed Immunotherapy
Marrit Putker, Saskia De Man, and Pirouz Daftarian from Crown Bioscience discuss T cell-directed immunotherapy on the cancer-immunity cycle, including mechanisms and targets capable of modulating and enhancing T cell activity and the application of methods and models including organoids and high content imaging.
#ExpertAnswers: Dudley Lamming on the Influence of Sex and Genetic Background on Diet
Dudley Lamming, PhD, explains that “We Are More Than What We Eat”; Sex and Genetic background are important factors in observing responses to diet in mice.
#ExpertAnswers: Phil Griffiths on Telemetry Studies
Phil Griffiths draws from his experience as a telemetry user to discuss some important considerations for designing telemetry studies.
#ExpertAnswers: Cole McLarty, Nick Glover, and Tim Hacker on Pressure-Volume Loops
Cole McLarty, Nick Glover and Dr. Timothy Hacker focus on Pressure-Volume Loop collection and data analysis for cardiovascular research.
#ExpertAnswers: George Portugal on Microelectrode Array Technology
George Portugal discusses microelectrode array (MEA) technology used for cardiac research and some best practices for integrating this technique into your research protocols.
#ExpertAnswers: Dennis Turner on the Metabolics of Dementia
Dennis Turner delves into dementia syndrome, the metabolic changes that occur, and the importance of proper physiological monitoring of animal models.
#ExpertAnswers: Rajendra Kumari and Gera Goverse on the Cancer Immunity Cycle
Rajendra Kumari and Gera Goverse provide an overview of the cancer immunity cycle and present several methods, techniques, and model systems for immuno-oncology research.
#ExpertAnswers: Oscar Perez Leal and Jon Weidanz on Gene Editing
Oscar Perez Leal and Jon Weidanz discuss the basis of the FAST-HDR gene-editing system to create custom cell lines, and present case studies highlighting several applications.
#ExpertAnswers: Amy Sheng on Antibody Screening and Discovery
Amy Sheng provides an overview of antibody screening platforms and presents applications and case studies using the Beacon® platform for antibody discovery.
#ExpertAnswers: Ejvind Mørtz on Protein Analysis
Ejvind Mørtz discusses the benefits and applications of mass spectrometry (MS)-based host cell protein (HCP) analysis and why HCP ELISAs are insufficient for documenting product-related impurities.
#ExpertAnswers: Andrew Taylor on Drug Metabolism
Andrew Taylor provides an overview of processes by which drugs are metabolized and talks about the importance of drug metabolism and drug-drug interaction studies.
#ExpertAnswers: Giacomo Rossitto on Heart Failure and Lymphatic Dysfunction
Giacomo Rossitto answers questions from a recent webinar where he shares his research on heart failure and the related lymphatic dysfunction in patients.
#ExpertAnswers: Jonathan Brestoff on Energy Expenditure
Jonathan Brestoff explains how energy expenditure can be better described thanks to a new bioinformatic algorithm known as Clambake.
#ExpertAnswers: Michael Sturek on Macrovascular Atherosclerosis and Microvascular Dysfunction
Michael Sturek reviews features of macrovascular atherosclerosis and microvascular dysfunction that underlie ischemic events and the need for appropriate animal models for optimal translation.
