Diego Bohórquez

Diego Bohórquez, PhD

Assistant Professor of Medicine
School of Medicine
Duke University

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Diego Bohórquez and his colleagues developed a transgenic mouse in which enteroendocrine cells of the distal ileum and colon are fluorescent and discovered prominent cytoplasmic appendages in these cells. Dr. Bohórquez subsequently coined the term neuropod to refer to these appendages. In September 2018, his laboratory published an article in Science documenting a new mechanism for the gut to transduce a sense to the brain in milliseconds. This newly uncovered sensory transduction mechanism uses glutamate as a neurotransmitter. It involves a synapse between enteroendocrine cells and vagal neurons. This research has been widely cited in the scientific and popular press.