Jonas Treebak, PhD
Novo Nordisk Foundation Center for Basic Metabolic Research
University of Copenhagen
Jonas Treebak is a physiologist studying molecular metabolism in humans and rodent models of metabolic disease. He obtained his PhD in skeletal muscle metabolism from University of Copenhagen, Denmark in 2009, and in 2011 he was appointed Group Leader at the Novo Nordisk Foundation Center for Basic Metabolic Research (CBMR), University of Copenhagen where he currently holds a position as Associate Professor. The research activities of his group are directed towards interrogating the signaling pathways controlling cellular and whole-body glucose and lipid homeostasis. To resolve physiological roles of genes, proteins, and pathways that regulate metabolism, transgenic animals with mutant and wild-type forms of candidate genes are applied. Over recent years, his focus has been on determining the importance of the NAD+ generating systems for the ability of cells to adapt to metabolic stress. In particular, the protein NAMPT has been investigated in skeletal muscle, liver, adipose tissue and the hypothalamus. His group is developing in vivo methodologies to assess the functional role of novel targets in metabolic diseases, and his is also coordinating the work in the Rodent Metabolic Phenotyping Platform at CBMR.