Leigh Goedeke, PhD
Yale School of Medicine
Dr. Leigh Goedeke is a Postdoctoral Fellow at Yale School of Medicine, in the laboratory of Dr. Gerald Shulman. With extensive experience in multiple metabolic disease indications, Dr. Goedeke specializes in the interplay between hepatic steatosis, insulin resistance, type 2 diabetes, and cardiovascular disease. As part of the Shulman lab, Dr. Goedeke uses stable isotope tracer methods to understand how alterations in metabolic fluxes contribute to the pathogenesis of insulin resistance and is investigating the therapeutic potential of liver-targeted mitochondrial uncoupling agents to reverse metabolic syndrome.
Dr. Goedeke received her Ph.D. in Biomedical Sciences from New York University School of Medicine where she identified and characterized novel genes and miRNAs involved in lipid metabolism using functional genomic screens. She has authored over 30 publications, and holds a patent in a specialized oligonucleotide as a therapeutic tool for treating dyslipidemias and cardiovascular diseases