Saran Lotfollahzadeh

Saran Lotfollahzadeh, MD

Research Scientist, General Surgeon, Pediatric Surgery Sub-Specialist
Renal and Vascular Research
Boston University


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I entered medical school through a highly competitive matriculation process overseas. I successfully graduated as a top student. In the continuum toward my goal, I embarked on the first-ranked integrated five-year general and vascular surgery residency program, where I graduated with the highest honor in the national board exam and research. Consequently, I started in the top-ranked pediatric surgery subspecialty clinical and research program. I led the first global gastrointestinal birth defect registry in collaboration with King’s College, London, England. The work is published in The Lancet (Global PaedSurg Research Collaboration. Lancet. 2021 Jul 24;398(10297):325-339. doi: 10.1016/S0140-6736(21)00767-4. Epub 2021 Jul 13. PMID: 34270932; PMCID: PMC8314066) Considering my salient achievements as the youngest double board-certified surgeon in the country, I joined the department of renal and vascular research at Boston University in October 2019. According to my work in vascular research, I was granted a strategically focused research fellowship by the American Heart Association in July 2021 to continue my research at Boston Medical Center on Cancer-Associated Thromboembolism as Affected by Health Disparities (CAT-HD). Since I joined Boston University in 2019, I have contributed to the publication of five seminal papers and more accepted for publication,1. Lotfollahzadeh S, Lo D, York EA, et al. Pharmacologic Manipulation of Late SV40 Factor Suppresses Wnt Signaling and Inhibits Growth of Allogeneic and Syngeneic Colon Cancer Xenografts [published online ahead of print, 2022 Jun 13]. Am J Pathol. 2022; S0002-9440(22)00170-5. 2. (Arinze et al., J Clin Invest. 2022; 3. Walker et al., J Am Soc Nephrol. 2021; 4. Amraei R et al., Proc Natl Acad Sci U S A. 2022), 5. Hartsough et al. iScience. 2022; July. Moreover, according to my passion for innovative animal models, I have developed a novel rodent model to optimize peritoneal catheters, which has been recently accepted for publication in the Journal of Visual Experiments. Additionally, I took the lead in collaborative research work with the department of biomedical engineering at Boston University to optimize and validate the application of animal models for renal fibrosis.