Studying Epilepsy in Awake Head-Fixed Mice Using Microscopy, Electrophysiology, and Optogenetics

Studying Epilepsy in Awake Head-Fixed Mice Using Microscopy, Electrophysiology, and Optogenetics

THU, OCT 8, 2020

Experts discuss how microscopy, electrophysiology, and optogenetics are used to study microglial calcium signaling and epileptic networks in awake head-fixed mice.

From Pregnancy to Menopause: Studies of Physical Activity, Behavior, and Energy Balance in Mice

From Pregnancy to Menopause: Studies of Physical Activity, Behavior, and Energy Balance in Mice

THU, OCT 1, 2020

Sharon Ladyman and Vicki Vieira-Potter share their research on the effects of hormones and pregnancy on daily activity in mice.

Case Studies in Home Cage Monitoring: Rodent Behavior, Circadian Biology and Animal Welfare

Case Studies in Home Cage Monitoring: Rodent Behavior, Circadian Biology and Animal Welfare

THU, SEP 24, 2020

Joanna Moore and Kenneth Dyar present applications of the DVC® system from different research perspectives and discuss how home cage monitoring can be used to study animal model development, physiology and behavior.

Functional Ultrasound (fUS) Imaging in the Brain of Awake Behaving Mice

Functional Ultrasound (fUS) Imaging in the Brain of Awake Behaving Mice

ON DEMAND

Experts discuss how functional ultrasound imaging in awake head-fixed mice can help advance basic neuroscience and neurovascular research, as well as preclinical drug discovery.

Improving Animal Modeling with 24/7 Home Cage Monitoring in Bioexclusion & Biocontainment Mouse Housing Systems

Improving Animal Modeling with 24/7 Home Cage Monitoring in Bioexclusion & Biocontainment Mouse Housing Systems

ON DEMAND

Experts discuss current biosafety requirements and what home cage monitoring can teach us in bioexclusion and biocontainment studies.

The Use of Home Cage Monitoring to Determine Whether Individual Male Mouse Activity Patterns Correlate with Nest Complexity

The Use of Home Cage Monitoring to Determine Whether Individual Male Mouse Activity Patterns Correlate with Nest Complexity

VIRTUAL POSTER

It is well established that nesting materials are an important inclusion for mouse cages. We wanted to determine whether there was a significant difference in mice activity when offered three different material choices and whether there was any correlation between activity in the cage and nest complexity.

Locomotor Activity: refinement, reduction and replicability ‘round the clock in animal studies

Locomotor Activity: refinement, reduction and replicability ‘round the clock in animal studies

VIRTUAL POSTER

A growing body of evidence suggests that Home Cage Monitoring studies are becoming key tools for in vivo animal research for three main reasons: reduction in animal distress thereby increasing welfare, minimization of biases (wanted and unwanted), and increased reproducibility of data.

Measuring Visual Acuity and Contrast Sensitivity by Optomotor Reflex in Rodents

Measuring Visual Acuity and Contrast Sensitivity by Optomotor Reflex in Rodents

ON DEMAND

Experts discuss case studies and experimental data from various applications using a newly developed automated system to measure vision based on the optomotor reflex.

Odor delivery with the 220A Olfactometer from Aurora Scientific

Odor delivery with the 220A Olfactometer from Aurora Scientific

TECH CAST

Chris Rand discusses the updated 200A Olfactometer from Aurora Scientific. He walks through setting up the system before sharing best practices, all while demonstrating the integral functions of the system.