Dr. Sarah-Jane Guild provides an introduction to optogenetics, discusses the advantages of implantable optogenetics telemetry and reviews data collection using the Kaha Sciences Optogenetics system.
Archive for: animal behavior
Improving Animal Modeling with 24/7 Home Cage Monitoring in Bioexclusion & Biocontainment Mouse Housing Systems
Experts discuss current biosafety requirements and what home cage monitoring can teach us in bioexclusion and biocontainment studies.
The Use of Home Cage Monitoring to Determine Whether Individual Male Mouse Activity Patterns Correlate with Nest Complexity
VIRTUAL POSTER
It is well established that nesting materials are an important inclusion for mouse cages. We wanted to determine whether there was a significant difference in mice activity when offered three different material choices and whether there was any correlation between activity in the cage and nest complexity.
Locomotor Activity: refinement, reduction and replicability ‘round the clock in animal studies
VIRTUAL POSTER
A growing body of evidence suggests that Home Cage Monitoring studies are becoming key tools for in vivo animal research for three main reasons: reduction in animal distress thereby increasing welfare, minimization of biases (wanted and unwanted), and increased reproducibility of data.
Measuring Visual Acuity and Contrast Sensitivity by Optomotor Reflex in Rodents
Experts discuss case studies and experimental data from various applications using a newly developed automated system to measure vision based on the optomotor reflex.
Odor delivery with the 220A Olfactometer from Aurora Scientific
TECH CAST
Chris Rand discusses the updated 200A Olfactometer from Aurora Scientific. He walks through setting up the system before sharing best practices, all while demonstrating the integral functions of the system.
Turn Away from Traditional Tethering and Towards a Better Method for Data Collection
Experts discuss the use of a novel movement responsive rodent caging system as a means to minimize animal stress and enable unique discovery in many research applications, namely neuroscience, animal behaviour, drug discovery and cardiometabolic disease.
Place Cell Mapping and Stress Monitoring in Head-Fixed Mice Navigating an Air-Lifted Homecage
Scientists present data on 2-photon imaging of hippocampal place cells and on stress monitoring in head-fixed awake behaving mice.
Understanding Physiological Mechanisms of Opioid Addiction: Advancements in CNS and Respiratory Endpoint Measurement
Experts discuss how opioids affect sleep and respiratory depression in preclinical mouse models.
Single-Cell Electrophysiology and 2-Photon Imaging in Awake Mice with 2D-Locomotion Tracking
Scientists present case studies featuring single-cell electrophysiology and 2-photon microscopy in head-fixed, behaving mice.
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