Experts present key considerations in the design of rigorous preclinical studies in rodent models of muscular dystrophy, including animal model selection, assays and endpoints, and how your results can inform translation to the clinic.
Archive for: muscular dystrophy
Dr. DeWayne Townsend and Dr. Adam Goodwill discuss the fundamentals of pressure-volume loop analysis as a means to study cardiac function.
Suzie Buono discusses the work she and her team have done to provide an example of treating a dominant disease by targeting both alleles, suggesting that this strategy may be applied to other dominant diseases.
Jordan Fuqua discusses how autophagy and proteolytic processes are regulated in skeletal muscle, specifically looking at ULK1 and ULK2 and their roles in maintaining skeletal muscle homeostasis, morphology, protein aggregate degradation and autophagy.
The MRL/MpJ mouse strain has been touted as a "superhealer" although different tissues have previously displayed different levels of healing ability. We sought to test that ability in skeletal muscle.
Matt Borkowski of Aurora Scientific discusses the latest software update for their Dynamic Muscle Control and Analysis Software, DMC LabBook.
Experts present key concepts regarding how gait can be studied and its value as a research method for animal models of pain, CNS, neuromuscular and neurodegenerative disorders.
An essential webinar for all muscle researchers interested in methodology, best-practices, and techniques for in-vivo, in-vitro, and in-situ muscle experimentation.