Tag: immunology

  • CrownBio Cancer-Immunity Cycle Blog FI

The Cancer-Immunity Cycle: Research Solutions for Preclinical Immuno-Oncology

News, Oncology|

Cancer immunotherapy has undoubtedly expanded the cancer treatment landscape and improved patient outlook, which can in part be attributed to the recognition of the importance of the cancer-immunity cycle as a whole. In this blog, we provide an overview of the cancer-immunity cycle and highlight some preclinical models that can facilitate cancer immunotherapy research.

  • HSV Skin-on-chip FI

Skin-on-Chip for Preclinical Herpes Disease Modeling

News|

Organs-on-a-chip are attractive alternatives for bridging the translational gap between preclinical and clinical stages in vaccine development, particularly for herpes simplex virus (HSV). In this blog post, we review an article from Nature Communications on a skin-on-chip device for modeling HSV infection, as well as evaluating immune responses and antiviral drug efficacy (featured image © 2022 Sun et al., licensed under CC BY 4.0).

  • Exosome secretion from cells

Inhalable COVID-19 Vaccines: Recent Findings and Breakthroughs

News|

Given that SARS-CoV-2 is primarily transmitted through respiratory droplets, with respiratory mucosa being the main viral entry route, is intramuscular administration the most effective vaccine delivery method to fight COVID-19? In this blog post, we have reviewed one recent study that reported the design and preclinical testing of an inhalable, exosome-based COVID-19 vaccine.

  • Diabetes and COVID

Does Diabetes Promote COVID-19, or Does COVID-19 Promote Diabetes?

News|

During the COVID-19 pandemic, many of those living with diabetes were required to follow strict guidelines to protect themselves against infection as they were at high risk of morbidity and mortality. This blog takes a look at the links between angiotensin-converting enzyme 2 (ACE2) expression and diabetes, as well as incident diabetes and long COVID.

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