Function and Dysfunction of TRPV4 Channels in the Alveolar Epithelium

Alexander Dietrich, Prof. Dr., Principal Investigator, Experimental Pharmacology, Walther-Straub-Institute, LMU-Munich

TRPV4 Temperature Sensitivity to Remote Control of Neurons

Ali Guler, PhD, Associate Professor of Biology, University of Virginia

Epidermal TRPV4 Ion Channels Regulate UVB Induced Sunburn by Triggering Inflammasome Activation and ERK Signaling

Carlene D. Moore, PhD, Associate Professor of Neurology, Duke University Medical Center

Gain-of-Function Mutation in TRPV4 Identified in Patients with Osteonecrosis of the Femoral Head

Chantal Séguin, MD, BSc(N), FRCPC, Associate Professor, Department of Medicine, McGill University Health Centre, Glen site, Cedars Cancer Centre

Synthetic Mechanogenetic Gene Circuits

Farshid Guilak, PhD, Professor, Orthopaedic Surgery, Washington University in St. Louis

Physiological Significance of TRPV4 in Glia Cells

Makoto Tominaga, MD, PhD, Professor, Division of Cell Signaling, National Institute for Physiological Sciences, Okazaki, Japan

Differential Roles of the Calcium Ion Channel TRPV4 in Host Responses to Mycobacterium Tuberculosis Early and Late in Infection

Avinash Sonawane, PhD, Professor, Department of Biosciences and Biomedical Engineering, Indian Institute of Technology Indore (IIT Indore)

Preclinical Studies Using TRPV4 Antagonists to Treat Hydrocephalus

Bonnie Blazer-Yost, PhD, Professor, Biology Department Indiana University – Purdue University Indianapolis

The Role of TRPV4 Ion Channels in Joint Pain

Frank Richter, apl. Prof. Dr, Scientific Assistant, Institute Physiology Neurophysiology, University Hospital Jena, Friedrich-Schiller University

Defining Functional Crosstalk Between TRPV4 and Pro-Inflammatory GPCRs

Nicholas Veldhuis, PhD, Senior Research Fellow, Drug Discovery Biology, Monash University

TRPV4 Activity in the Distal Nephron Controls Systemic K+ Homeostasis

Oleh Pochynyuk, PhD, Associate Professor, Integrative Biology and Pharmacology, University of Texas Health Science Center at Houston

Epithelia-Sensory Neuron Crosstalk Underlies Cholestatic Itch Induced by Lysophosphatidylcholine

Yong Chen, PhD, Assistant Professor, Neurology, Duke University Medical Center

TRPV4 Channels in Neural Circuits Mediating Fluid Homeostasis

Charles Bourque, PhD, Professor, Neurology Neurosurgery, Research Institute McGill University Health Center

Endothelial TRPV4 Channels Prevent Tumor Growth and Metastasis via Modulation of Tumor Angiogenesis and Vascular Integrity

Charles Thodeti, PhD, Associate Professor, Integrative Medical Sciences, Northeast Ohio Medical University

Interrogate Molecular Functions at the Organism Level

Li Ye, PhD, Assistant Professor, Neuroscience, The Scripps Research Institute

The Role of TRPV4 in Lower Urinary Tract Pathways with Bladder Inflammation or Following Spinal Cord Injury

Margaret Vizzard, BA, PhD, Professor and Vice-Chair of Education, Neurological Sciences, Larner College of Medicine at The University of Vermont

Mechanosensitive Ion Channels in Confined Cell Migration

Miguel A. Valverde, PhD, Professor of Physiology, Experimental Sciences and Health, Universitat Pompeu Fabra

Oxidative Stress Mediates Thalidomide-Induced Pain by Targeting Peripheral TRPA1 and Central TRPV4

Romina Nassini, PhD, Professor, & Francesco De Logu, PhD, Scientific Researcher, Health Sciences, University of Florence

Mechanical Activation of TRPV4 in the Cell-Substrate Interface

Kate Poole, PhD, Associate Professor, Single Molecule Science, University of New South Wales

Structural Insights into TRPV4 Function

Peng Yuan, PhD, Associate Professor, Cell Biology and Physiology, Washington University School of Medicine

Role of TRPV4 in Pancreatitis

Rodger Liddle, MD, Professor of Medicine, Medicine, Duke University

TRPV4 in Modulating Environmental Effects on NAFLD

Saurabh Chatterjee, PhD, Associate Professor, Departments of Environmental Health and Medicine, University of South Carolina

Activation Modes by Different Agonists in TRP Channels

Tamara Rosenbaum, PhD, Professor, Cognitive Neuroscience, National Autonomous University of Mexico

TRPV4 – A Key Regulator of Endothelial Barrier Function in the Lung

Wolfgang Kuebler, MD, Professor, Institute of Physiology, Charité – Universitätsmedizin Berlin

TRPV4 and Mechanosensory Signaling in Astrocytes

Alexander Gourine, PhD, Professor of Physiology, Neuroscience, Physiology and Pharmacology, University College London

Mechanisms Underlying Neurogenic TRPV4 Channelopathies

Charlotte Sumner, MD, Professor of Neurology and Neuroscience, Johns Hopkins University School of Medicine

Defining TRPV4 Expression and Function in the Gastrointestinal Tract

Daniel Poole, PhD, Research Fellow, Drug Discovery Biology, Monash Institute of Pharmaceutical Sciences

A 20-year Journey Discovering the Physiology of TRPV4 in the Regulation of Endothelial Barrier Properties

Diego Alvarez MD, PhD, Professor and Chair, Physiology and Pharmacology, Sam Houston State University

Role of TRPV4 in Foreign Body Response to Biomaterials

Shaik Rahaman, PhD, Associate Professor, Nutrition and Food Science, University of Maryland

The Gut Brain Axis and Chronic Visceral Pain

Stuart Brierley, PhD, Professor, Visceral Pain Research Group, Flinders University

Beyond Photons: TRPV4 as a Key Regulator of Mechanosensing and Signaling in the Healthy and Diseased Eye

David Krizaj, PhD, Professor, Ophthalmology & Visual Sciences, University of Utah

Oxidative Stress Mediates Thalidomide-Induced Pain by Targeting Peripheral TRPA1 and Central TRPV4

Francesco De Logu, PhD, Scientific Researcher & Romina Nassini, PhD, Professor, Health Sciences, University of Florence

Activation of TRPV4 on Dural Afferents Produces Headache Behavior in a Preclinical Rat Model

Greg Dussor, PhD, Associate Professor, Neuroscience, University of Texas at Dallas

Mechanosensation in Macrophages Protects the Lung from Infection-Associated Lung Injury via TRPV4-Rac1-MAPK Axis

Rachel Scheraga, MD, Assistant Professor of Medicine, Respiratory Institute: Pulmonary and Critical Care Medicine, Cleveland Clinic

TRPV4 Inhibition, a Potential Strategy to Prevent Increased Water Diffusion and Blood-Retina Barrier Breakdown in the Diabetic Retina

Stéphanie Thébault, PhD, Permanent Researcher, Neurobiology of Development and Neurophysiology, UNAM

TRPV4 Channel-Dependent Signaling Microdomains in the Vasculature

Swapnil Sonkusare, PhD, Assistant Professor, Physiology, University of Virginia

Role and Mechanism of TRPV4-PI3Kgamma Interactions in Myofibroblast Differentiation and Pulmonary Fibrosis

Mitchell Olman, MD, MA, Professor of Molecular Medicine, Inflammation and Immunity, Lerner Research Institute- Cleveland Clinic

Unveiling the Role of TRPV4 in Astrocytes by Leveraging Optical, Electronic and Advanced Materials Tools: More Translational Progress Ahead

Valentina Benfenati, Ph.D, Senior Researcher, Institute for Organic Synthesis and Photoreactivity, National Research Council

TRPV4 Blocker GSK2798745: Pioneering the Clinical Path

David Behm, MS, Senior Director, Early Development Leaders, GSK

TRPV4 as a Target to Counteract Lung Injury: Studies in Chemical Injury Models

Sven-Eric Jordt, PhD, Associate Professor, Anesthesiology, Duke University

Videocystometry Shines Light on the Role of TRPV4 Channels in the Lower Urinary Tract

Thomas Voets, PhD, Professor, Department of Cellular & Molecular Medicine, KU Leuven

TRPV4 as Novel Target for Preterm Labor

David Cornfield, MD, Professor, Pediatrics – Pulmonary Medicine, Stanford University