WEBINAR SERIES – Preclinical Cardiovascular Science 2018
An overview of in vivo, ex vivo and in vitro research instrumentation, trending lab methods, best-practices and exciting research case studies focused on preclinical models of cardiovascular function and hemodynamics research.
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Advances in laboratory instrumentation for cardiovascular research have provided scientists with a multitude of technologies for monitoring function in both anesthetized and conscious animals in vivo. Functional assays using isolated heart preparations, vessels, and cardiomyocytes provide additional layers of scientific investigation, all contributing to a deeper understanding of basic cardiovascular physiology, cardiomyopathy, translational science and potential treatment modalities for heart related illness. The purpose of this webinar series is to provide an overview of current trends and advancements in the field of preclinical cardiovascular research.
Thank you to all that participated in this webinar series. To view content on-demand please visit the individual event pages listed below and sign in.
Experimental Considerations when Planning Chronic Models of Cardiovascular Disease in Rodents
Join Dr. Tim Hacker for a discussion on experimental design, strategy, technology, common challenges and best-practices associated with planning long-term, chronic models of cardiovascular disease in rodents.
Techniques and Best Practices for Cardiomyocyte Isolation
Ronglih Liao and Davor Pavlovic discuss techniques for isolating myocytes using both traditional and Langendorff-free methodologies, including key considerations, best practices and how to achieve and confirm optimal myocyte quality
Combining Telemetry and Ultrasound for Serial Investigation of Cardiovascular Function in Rats
Experts discuss a novel method of recording serial measurements of cardiac function in rodents using high-resolution ultrasound paired with implantable telemetry.
Improving Preclinical and Clinical Regulatory Submissions Through Enhanced ECG Interval and Arrhythmia Assessment
Experts in preclinical and clinical ECG safety assessment discuss how advances in arrhythmia detection and concentration effects modelling improve study outcomes.
- Creating models of Heart Failure
- HFpEF vs HFrEF
- Myocardial Infarction
- Trans-Aortic Constriction
- Cardiac Remodeling
- Pulmonary Hypertension
- Preload, Afterload, Contractility and Lusitropy
- Ventricular-Vascular Interactions
- Studying Blood Flow and Blood Pressure
- Integrating noninvasive and invasive experimental design
- Cardiovascular Safety Pharmacology
- Invasive Blood Pressure & Blood Flow Sensors
- Cardiac Imaging Systems
- Myocyte Calcium-Contractility Systems
- Pressure-Volume Loop Systems
- Noninvasive Blood Pressure and Flow Systems
- Implantable, Wireless Telemetry
- Isolated Heart Systems (Langendorff and Working Heart)
- Surgical Equipment & Vital Sign Monitors for Invasive Cardiac Procedures