Cardiovascular Autonomic Dysfunction in the Post-COVID Landscape: Detection and Management
Artur Fedorowski, MD, PhD, describes cardiovascular dysautonomia in COVID-19 and the diagnostics behind detecting Long COVID or Post-acute Sequalae of COVID-19.
The 3D DILI Model of Success – from Biological Relevance to Industry Application
Dr. Anna Borgström and Dr. Frauke Greve present the latest advancements in hepatic safety assessment using 3D liver spheroids.
APS Physiology in Disease Modeling and Drug Development Roundtable
Key opinion leaders in cardiovascular physiology and bioengineering discuss best practices and challenges when modeling cardiomyopathies and other cardiovascular diseases using stem cells, engineered tissues and other novel platforms.
It’s Life, but Not As We Know It: How Predictive Human Organ Models Are Transforming and Reshaping the Efficiency of Drug Discovery
Dr. Audrey Dubourg and Dr. Gareth Guenigault explore the value that an organ-on-a-chip approach can bring to drug discovery and development workflows, and how the regulatory landscape is shifting to encourage their widespread adoption.
Understanding Intracranial Pressure in Freely Moving Rats
Join Connar Westgate, PhD for a deep dive into intracranial pressure measurements and the importance of understanding this physiological parameter for maintaining normal CNS function.
Functional Recovery of the Musculoskeletal System Following Injury – Leveraging the Large Animal Model
Watch Dr. Sarah Greising discuss the current pathophysiologic understanding of the skeletal muscle remaining following traumatic musculoskeletal injuries.
Designing Causal Inference Studies Using Real-World Data
In this webinar, experts provide an overview of causal inference, along with step-by-step guidance to designing these studies using real-world healthcare data.
Streamlining Health Technology Assessments by Automating Literature Reviews
Experts provide a deep dive into what Health Technology Assessment (HTA) agencies do and the types of literature reviews they do.
Social Media Data: Opportunities and Insights for Clinical Research
Hear four experts from ICON and Kap Code provide insights on how to collect, use, analyze, and interpret social media data in different contexts. These experts share knowledge from over fifteen years of successfully developing and adapting algorithms to treat this kind of data.
We Are More Than What We Eat: Dietary Interventions Depend on Sex and Genetic Background
Dudley Lamming, PhD, explains how sex and strain type are highly important factors in observing responses to dietary interventions in mice.
In Vivo Modeling of Immune-mediated Optic Neuropathies
Oliver W. Gramlich, PhD, provides an in-depth discussion about the pathobiology and visual phenotype of immune-mediated optic neuropathies.
Antibody Discovery by Single B Cell Screening on Beacon®
Amy Sheng, PhD provides an overview of antibody screening platforms and presents applications and case studies using the Beacon® platform for antibody screening.
Strategic Approaches to Age-Related Metabolic Insufficiency and Transition into Dementia Syndrome
In this webinar, Dr. Dennis Turner delves into dementia syndrome, the metabolic changes that occur, and the importance of proper physiological monitoring of animal models.
Clambake: Decoding Factors That Contribute to Energy Expenditure
Join Jonathan Brestoff, MD, PhD, MPH, for an exploration of how energy expenditure can be better described thanks to a new bioinformatic algorithm known as Clambake.
Experimental Design Considerations to Optimize Chronic Cardiovascular Telemetry Studies
Phil Griffiths, PhD, presents a summary of chronic cardiovascular telemetry studies and considerations for experimental design.
Creating Better Gene-Edited Cell Lines with the FAST-HDR System
Dr. Oscar Perez and Dr. Jon Weidanz discuss the basis of the FAST-HDR gene-editing system and present case studies highlighting several applications.
Achieving Consensus When Everyone is an Expert, but No One Agrees
Watch experts from PHAR, Novartis, and Bausch Health discuss the Delphi panels and how the results are used.
Accelerating the Generation of Payer Insights and Evidence Across the Product Lifecycle to Achieve Optimal Access
Experts present opportunities for using agile platforms and fit-for-purpose engagement models that can drive an iterative approach to obtaining payer insights and developing impactful evidence generation strategies.
Beyond the Familial: The Development of Emotional Communication with Mothers, Fathers, and Strangers
Join Eliala Salvadori, MSc for a discussion on her research involving infant emotional communication patterns.
Making HEOR More Accessible to Patients
Watch this panel discussion to hear experts from patient advocacy, health literacy, and Health Economics and Outcomes Research (HEOR).
Are In Vitro Metabolism and Drug-Drug Interaction Studies Critical for an Investigational New Drug Application?
Andrew G. Taylor, PhD provides an overview of processes by which drugs are metabolized and discusses the importance of drug metabolism and drug-drug interaction studies.
An Introduction to Infectious Disease Modeling
Hear ICON experts give an in-depth overview of infectious disease modeling with a focus on assessment of interventions and its challenges.
Cardiometabolic Disease Pathophysiology & Novel Therapies for Atherosclerosis & Calcification
In this webinar, Dr. Michael Sturek reviews features of macrovascular atherosclerosis and microvascular dysfunction that underly ischemic events and the need for appropriate animal models for optimal translation.
Intestinal Toxicity Assessment with Patient-Derived Organoids
Dr. Martin Stahl describes the use of patient-derived intestinal organoids to assess the toxicity of potential therapeutic compounds and study barrier function in a human-specific model system.
Syapse Real-World Dialogue: Advancing Patient Care through Real-World Data, Machine Learning, and Systems Biology
Join Drs. Nitin Baliga and Thomas Brown for an in-depth discussion on utilizing real-world data, machine learning, and systems biology for benefiting therapeutic development.