In this 2-part webinar, Dr. Dan Burkhoff provides an overview of the fundamental principles of preload, afterload, contractility and lusitropy (diastolic properties), how these are quantified on the pressure-volume diagram, and how they are affected in heart failure.
Part 1: Fundamentals
After reviewing measurement techniques and underlying properties of cardiac muscle and ventricular structure, Dr. Burkhoff demonstrates how pressure-volume analysis can lead to a quantitative understanding of how the heart and vasculature interact to determine stroke volume, cardiac output and blood pressure. The implications for understanding therapeutic effects are also discussed.
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Director of Heart Failure, Hemodynamics and Circulatory Support
Cardiovascular Research Foundation