In this 2-part webinar, Dr. Dan Burkhoff provides an overview of the fundamental principles of preload, afterload, contractility and lusitropy (diastolic properties), how these are quantified on the pressure-volume diagram, and how they are affected in heart failure.
Part 1: Fundamentals
After reviewing measurement techniques and underlying properties of cardiac muscle and ventricular structure, Dr. Burkhoff demonstrates how pressure-volume analysis can lead to a quantitative understanding of how the heart and vasculature interact to determine stroke volume, cardiac output and blood pressure. The implications for understanding therapeutic effects are also discussed.
Part 2: Advanced Concepts
A continuation of Part 1, advanced concepts of Pressure-Volume Analysis are discussed including best-practices to follow in the lab during data acquisition and statistical analysis. This webinar also includes an extended Q&A session with Dr. Burkhoff, where he also addresses questions from the audience received during seminar one.
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Adjunct Clinical Professor of Internal Medicine,
The Ohio State University Medical Center,
Vice President – Medical Science,
Heartware Internationl, Inc
Director of Heart Failure, Hemodynamics and Circulatory Support,
Cardiovascular Research Foundation
Founder, PVLoops LLC