Experts provide insight into high-throughput cognition testing of individual rodents within their social environment, discussing how this supports increased animal welfare and decreased data variability and workload for the researcher.
During this exclusive webinar sponsored by, TSE Systems, Drs. Ewelina Knapska, David Wolfer, and Holger Russig review automated home-cage behavioral phenotyping using the IntelliCage system and discuss several research applications including the study of hippocampus-dependent spatial learning tasks, measuring motor impulsivity, studying the role of MMP-9 in the central amygdala in learning of appetitively and aversively motivated behaviors, and assessing cognitive rigidity in a mouse models of autism.
After establishing basic concepts, presenters demonstrate how freely programmable behavioral tasks can be controlled and how to link them to established paradigms performed in biomedical and basic behavioral, neurobiological, psychiatric, pharmacological and genetic research. The implications for understanding therapeutic strategies is also discussed.
Resources
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Presenters
Associate Professor of Anatomy
Institute of Anatomy
University of Zurich
Laboratory of Emotions Neurobiology
Nencki Institute of Experimental Biology
Scientific Officer
TSE Systems Inc.