Watch Eduardo Marbán, MD, PhD give a deep dive into the complexities of regenerative cardiovascular medicine and the future directions for cell therapies.
Dr. Marbán’s lab has found several noncoding RNA (ncRNA) species, including short Y RNAs, which themselves have intriguing biological actions. The ncRNA within extracellular vesicles can either be used as they occur naturally or serve as bioinspiration for new chemical entities. The next generations of cell-free biologics (extracellular vesicles and noncoding RNAs) may provide, or even transcend, the benefits of cell therapy without the intrinsic limitations.
Key Topics Include:
- Understand the current status of cell therapy for heart disease
- Review the mechanisms whereby cells exert their therapeutic benefits
- Explore the future of RNA drugs inspired by the contents of extracellular vesicles
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Smidt Heart Institute
Cedars-Sinai Medical Center