An expert from AstraZeneca will discuss the use of antibody drugs, how they function and the different techniques used to characterize them in the drug development process.
This is the fourth of five events in the Bruker COVID-19 Webinar Series.
During this webinar, Dr. Maurizio Muroni from Astra Zeneca, will deliver an introduction on what antibodies are, their structure and an overview of some of the analytical techniques used for their structural characterization.
Dr. Maurizio Muroni was born in Sardinia where he gained a Laurea in Chimica, from University of Sassari, with a thesis on “Cyclic peptides (D, L alternate): synthesis, conformational analysis and molecular modelling”. Following, he moved to Cardiff where he graduated from a PhD in Biochemistry, Cardiff University – School of Chemistry, with a thesis on “ Rational design of artificial enzymes. After his PhD, Maurizio moved to London for an Industry based post doc between PolyTherics (now Abzena) and the School of Pharmacy, developing mass spectrometric methods for the characterization of PEGylated proteins. After two years he joined PolyTherics as Team Leader of Analytical Chemistry. And from 2014, he has been working at MedImmune/AstraZeneca as scientist working on the characterization of therapeutics protein in the Physiochemical Development team.
Additional Content From Bruker Corporation
Unlocking Your Clinical Understanding of Post-Acute COVID Syndrome (PACS), Patient Recovery, and Risk of Subsequent Disease
Watch this webinar to learn about the metabolic changes during COVID-19 disease, how these can be accurately tracked and how NMR can improve the clinical understanding of Long-COVID.
Cardiac PET/MR Imaging in Small Rodents
Experts provide a comprehensive overview of approaches to address cardiac and respiratory gating in PET and MRI in rodent models.
SmartDriveNMR – The Next Generation of Automation
Bruker experts provide an overview of SmartDrive with a particular focus on the exciting new features. They offer practical examples and demonstrate the newest features and functions live!
Fast-Forward Your Custom Antibody Generation With Four Bio-Rad Services
Discover how Bio-Rad's bioanalytical services and SpyTag-SpyCatcher technology can speed up custom antibody generation and improve assay flexibility for challenging targets.
Rethink your Impurity Analysis Strategy
In this webinar, Dr. Ejvind Mørtz discusses the benefits and applications of mass spectrometry (MS)-based host cell protein (HCP) analysis and why HCP ELISAs are insufficient for documenting product-related impurities. Watch to learn where to apply the assay in a typical process and what you gain from deploying it to your workflow.
Exploring Oligomerization and Stoichiometry of Protein Complexes with MALS: Case Studies from Phage-Bacteria Conflict
Experts discuss the utility of SEC-MALS in characterizing protein oligomerization and how it can complement protein structure determination and prediction tools.