Prof. Frank Schaeffel as he discusses the optical principles, image processing algorithms, calibration, and potential pitfalls within IR photorefraction and IR photokeratometry.

Commercial autorefractors and keratometers have enabled accurate measurement of refractive states and corneal power maps in humans for decades. However, making such measurements in small animal eyes  – such as mice, rats, guinea pigs, and even chickens – was a persistent problem until Prof. Frank Schaeffel developed and first published his work on Eccentric Infrared (IR) Photorefraction in 1986 (Vision Research). 

With the technique being continuously improved through the 90’s, a significant milestone was achieved in 2002 when it was successfully applied to mouse eyes for the first time.  Today, IR Photorefraction remains the only available refraction technique for small animal research and has been successfully adopted by many labs around the world. 

During this webinar, Prof. Schaeffel provides a full history and technical overview of IR Photorefraction and Photokeratometry.  He highlights fundamental optical principles of both techniques, reviews important image processing algorithms, details equipment calibration, and discusses potential pitfalls that all labs’ interested in these techniques will want to know about and avoid.  The webinar includes a Q&A with Prof. Schaeffel, providing an excellent opportunity to receive expert advice on the successful implementation and application of these techniques.  

Key Topics Include:

  • History of infrared photorefraction and photokeratometry
  • Application of refraction based eye measurement technique
  • Application of IR photokeratometry to measure corneal radius of curvature
  • Product calibration for optimal results

Who Should Attend?

Those interested in the study of myopia, measurement of small animal corneas, and eye growth.

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Institute of Opthalmic Research
University of Tübingen

Frank Schaeffel is a senior professor since 2019 and guest professor at the Institute of Molecular and Clinical Ophthalmology Basel (IOB) since 2020. In the IOB Myopia Research Group, Frank Schaeffel works with other scientists to develop and study visual stimuli to reduce eye growth. This research involves human subjects and also studies visual control of eye growth in mouse models.

Webinar Host


Striatech is a young biotech company that spun off from the University of Tübingen, Germany, at the beginning of 2018. The founders – a team of neurobiologists – are all experienced vision researchers and have made it their common goal to make innovative ideas and products from vision and behavioral research accessible to scientists worldwide.

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