The Application of NMR for Drug Development and Manufacturing in a Good Manufacturing Practice Setting

The Application of NMR for Drug Development and Manufacturing in a Good Manufacturing Practice Setting

Join Dr. Kerry Hughes, technical leader from Almac, for a presentation on the application of NMR in GMP settings to ensure high-quality performance of drug discovery workflows.

The use of Nuclear Magnetic Resonance (NMR) in GMP settings is extremely valuable: when applied correctly it helps to confirm the identity, strength, quality and purity of drug products and plays a key role in the production of reproducible drug discovery workflows.

In this webinar sponsored by Bruker BioSpin, Dr. Kerry Hughes, Technical Leader at Almac, discusses the convenience of utilizing NMR during various stages of the drug development process. She also reviews the importance of instrumentation qualification and routine performance checks, and shares specific examples of how Almac is using NMR to meet GMP regulations.

Key topics covered during this webinar include…

  • The versatility, convenience and accessibility of NMR
  • NMR in a GMP environment requires qualification and controls to ensure continued high-quality performance
  • Using NMR for supplier qualification, method validation, quantification of residual solvents and full structural elucidation of small molecules and peptides
  • How Almac is using the Bruker 400 AVANCE with QNP probe and 500 AVANCE NEO with prodigy cooled CryoProbe in its GMP setting

Dr. Kerry Hughes

Technical Leader
Almac

Dr Kerry Hughes is technical leader and NMR senior analytical chemist at Almac in Craigavon, County Armagh in Northern Ireland. Kerry has been working for the Almac group for four years. Before this, she completed a PhD in medicinal and pharmaceutical chemistry at Queen’s University in Belfast.