Turn Away from Traditional Tethering and Towards a Better Method for Data Collection

Experts discuss the use of a novel movement responsive rodent caging system as a means to minimize animal stress and enable unique discovery in many research applications, namely neuroscience, animal behaviour, drug discovery and cardiometabolic disease.

Novel environments (cage changes), traditional handling, restraint methods, and even the presence of humans can cause stress to laboratory animals. Minimizing stress to animals throughout the duration of a study is key to generating accurate, reproducible data while also improving animal welfare. BASi’s Raturn^TM is a movement responsive caging system that facilitates data collection in awake, freely moving rodents without the need for human intervention! Unlike swivels, this allows for simultaneous collection of multiple types of data that can be obtained from study animals, making it a useful tool for any researcher conducting tether-based studies.

During this webinar sponsored by BASi, Candace Rohde-Johnson will discuss how tethering systems can be used as a hands-off approach to data collection for research applications including microdialysis, open flow microperfusion, telemetry and optogenetics.

Following, Dr. John Cirrito, leading Alzheimer’s disease researcher and professor at Washington University of St. Louis, will present an overview of the data his team has collected through an in vivo microdialysis technique that enables minute-to-minute measurement of interstitial fluid (ISF) Aβ within the brains of awake and behaving mice. He will also share additional study applications made possible by using the Raturn^TM system.