Dylan Sarver and Matthew Borkowski show how to study the mechanical properties of tendon and connective tissue samples by completing stress/strain assays using a novel Dual-Mode Lever System.
Characterizing the mechanical properties of tendon and other connective tissue allows us to better investigate the very profound ways that parameters such as sex, aging, and injury affect our bodies.
In this webinar presented by Aurora Scientific, Matthew Borkowski and Dylan Sarver discuss how to characterize the structural and functional properties of tendon. Specifically, Mr. Borkowski describes the engineering behind the multi-purpose Aurora Scientific Dual Mode Lever — a fast actuator and sensitive force transducer in one — and how this device can be used to study connective tissue.
Following, Mr. Sarver discusses his current research focused on sex-related differences in the structural and functional status of Tendon, from macromolecular structural properties to transcriptomic, proteomic, and cell biology of resident tendon fibroblasts. He explains why tendon research is important, reviews methodology for investigating tendon structure and function, and discusses research findings supporting sex-related differences in tendon.
Key topics covered during this webinar will include…
- How to use The Dual-Mode Lever to perfom demanding stress/strain assays
- What is a tendon, and why is tendon research important
- How to characterize the structural and functional status of tendon
- Case Study: investigating sex-related differences in tendon
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University of Michigan
Dylan Sarver studied Biology and Chemistry at Millersville University of Pennsylvania and Athletic Training at West Chester University of Pennsylvania. He is a certified Athletic Trainer working full time as a Orthopeadic Research Associate at University of Michigan in the laboratory of Chris Mendias. His research focuses are muscle and tendon physiology and disease. To learn more about the research that Dylan is involved in, visit The Mendias Laboratory website.
Aurora Scientific Inc.
Matthew Borkowski is a biomedical engineer and a graduate of the University of Toronto. He has been involved in product design and customer support at Aurora Scientific for over 10 years. Today, he spends much of his time in the lab consulting with scientists, assisting with novel application of Aurora Scientific instruments in various disciplines, including muscle, tendon, and connective tissue research. To learn more about the instrumentation and application areas that Aurora Scientific serves, visit their website.