In this episode of Expert Answers join Dr. Tim West and Matt Borkowski for a discussion on how to properly isolate and prepare, and assess muscle performance and contractile function in single muscle fibers.
Join Patrick Schönleitner, PhD and Francisco Altamirano, PhD as they share their work involving simultaneous measurements of intracellular calcium, membrane voltage, and contractility of cardiomyocytes.
Dr. Charlotte Peterson and Dr. Jack Guralnik will discuss the challenges of sarcopenia. They will define the disease and provide an in depth overview of the underlying mechanisms of pathology. They will then share some potential therapeutic interventions and disease outcomes for patients.
Abstract coming soon! The Bodine laboratory is interested in identifying the mechanisms responsible for muscle atrophy and determining strategies for preventing atrophy or accelerating recovery following a period of muscle loss.
Julio Ayala, PhD and Matthew Robinson, PhD share their research focusing on feeding behavior in mice and the effects of stress and exercise on metabolism. They will discuss neuronal activity and high-fat diets as well as mitochondrial remodeling and exercise training in mouse models of obesity.
Experts present key considerations in the design of rigorous preclinical studies in rodent models of muscular dystrophy, including animal model selection, assays and endpoints, and how your results can inform translation to the clinic.
Suzie Buono discusses the work she and her team have done to provide an example of treating a dominant disease by targeting both alleles, suggesting that this strategy may be applied to other dominant diseases.
Jordan Fuqua discusses how autophagy and proteolytic processes are regulated in skeletal muscle, specifically looking at ULK1 and ULK2 and their roles in maintaining skeletal muscle homeostasis, morphology, protein aggregate degradation and autophagy.
Aaron Stupica and Keshari Thakali discuss techniques tissue bath myography and present a unique case study looking at the effect of maternal obesity on offspring perivascular adipose tissue and vascular function.
Building on its popular Biomechanics 101 Introduction, Noraxon turns it attention to the fundamental pillar of biomechanics: electromyography, or EMG. This informative session covers signal origin, acquisition, processing and analysis for a comprehensive and practical understanding of EMG research and assessment.