Experts present key considerations in the design of rigorous preclinical studies in rodent models of muscular dystrophy, including animal model selection, assays and endpoints, and how your results can inform translation to the clinic.
OBESITY SERIES 2020: Zhen Yan and Diego Bohórquez present case studies demonstrating the use of automated home cage phenotyping for preclinical obesity research.
Dr. Malmstrøm demonstrates how correlations between NMR data and bioactivity can be used to confirm the structure and activity of proteins.
Join Dr. Burgués as he demonstrates how he has built faster and more reliable MOX sensors for tracking turbulent chemical plumes.
Dr. Artur Fedorowski outlines the practical skills needed to perform a successful cardiovascular and autonomic workup in unexplained syncope and cardiovascular dysautonomia.
OBESITY SERIES 2020: Join Katsu Funai to learn how mitochondrial membrane lipids can affect metabolic efficiency and propensity for obesity-related diseases.
Carl Petersen and Alexei Verkhratsky share their research on homeostatic neuroglia and imaging of neuronal network function.
OBESITY SERIES 2020: Dr. Fred Beasley provides an overview of study design, criteria for defining your study aim and expert advice for selecting the ideal rodent model for your preclinical obesity research.
A webinar series focused on late-breaking research and discovery relating to the physiological mechanisms of obesity-related disease.
An expert in pharmaceutical sciences discusses solid-state NMR spectroscopy as an advanced analytical technique to provide unique insight into the composition and properties of pharmaceutical formulations.
Renowned MRI expert, Prof. Jim Wild, will discuss the clinical applications of 129Xe lung imaging with a focus on novel pulmonary therapies using hyperpolarized gas and proton lung MRI as markers.
OBESITY SERIES 2020: Camilla Schéele & Christian Wolfrum discuss the physiology of brown adipose tissue and share late-breaking research on the role of BAT in whole body metabolic regulation.
Dr. Dasgupta explains his unique methodology and applications for analyzing the temporal structure of odour plumes.
An infectious lung disease expert shares compelling evidence for the use of micro-CT to repeatedly evaluate disease progression and therapy efficacy in live animals.
Ole Petersen, Roop Mallik and Erwin Neher share the latest research looking at endocytosis and calcium signaling in the context of SARS-CoV-19, organelle transport and calcium imaging.
Experts discuss how functional ultrasound imaging in awake head-fixed mice can help advance basic neuroscience and neurovascular research, as well as preclinical drug discovery.
Experts discuss the synergies and implementation of state-of-the-art hybrid PET/MR technology and the new avenues of exploration it affords in the fields of neuroscience, cancer, and metabolic disease through to dual molecular probe development.
OBESITY SERIES 2020: Kevin Hall, PhD discusses the physiology of body weight regulation and how dietary factors like amount of carbs, fat and "ultra-processed" foods affect human body weight.
OBESITY SERIES 2020: Marshall McCue, PhD presents case studies using small mammals where 13C-labeled nutrient oxidation is tracked second-by-second in real-time using the newest laser-based stable isotope approaches.
Explore CrownBio's virtual American Diabetes Association 2020 event to catch up with the latest preclinical research on diabetes, NAFLD/NASH, obesity, cardiovascular and renal diseases.
OBESITY SERIES 2020: Lora Heisler, PhD discusses the unique brain circuits that are controllers of body weight, reviews how our genes impact our waistline and explains how obesity medications leverage basic neurobiology to reduce hunger and decrease body weight.
An expert from AstraZeneca will discuss the use of antibody drugs, how they function and the different techniques used to characterize them in the drug development process.
Attend this webinar to learn how VO2max exercise testing can be used to assess the cardiometabolic phenotype of rodents.
Dr. Redente discusses the advantages of microCT and provides a broad overview of pulmonary disease imaging using a highly innovate technique to analyze living animals, as well as fixed tissue.
Join Dr. Anna Honko and Dr. Doug Reed as they discuss methods and applications for infectious disease research including coronavirus-based illnesses.
Experts provide a guided tour to PET image reconstruction for the application-oriented user. They share the pros and cons, and give you a glimpse of what to expect in the future with exciting insights into future trends.
Experts discuss current biosafety requirements and what home cage monitoring can teach us in bioexclusion and biocontainment studies.
Dr. DeWayne Townsend and Dr. Adam Goodwill discuss the fundamentals of pressure-volume loop analysis as a means to study cardiac function.
Scientists discuss the use of NMR to analyze the antiviral drug Azidothymidine AZT, a medication currently used to prevent and treat HIV/AIDS.
Experts discuss how PET/CT imaging can be used to enable image-guided neurointerventions and to study targeted delivery and clearance of therapeutic agents.
Dr. Sarah-Jane Guild provides an introduction to optogenetics, discusses the advantages of implantable optogenetics telemetry and reviews data collection using the Kaha Sciences Optogenetics system.
Dr. Rohan Virgincar gives insight into the fundamentals of hyperpolarized 129Xe MRI and shares practical considerations for high-resolution imaging in rodent models of lung disease.
Experts discuss the ease of use and advantages to using a harmonized approach of Nuclear Magnetic Resonance and Mass Spectroscopy for the detection and identification of narcotics.
Dr. Francesco Berti describes the use of proton NMR for structural identity and conformity testing of carbohydrate-based vaccines.
Join BIOPAC to learn how you can get started with your own physiology research using VR, what options are available and how to create a virtual environment for physiology experiments.
NMI experts describe quality control procedures and image corrections for the Bruker PET technology, demonstrate image transfer to PMOD for analysis and outline best practices to ensure good quantitative PET.
Dr. Niamh O'Boyle, from Trinity College in Dublin, provides an overview of the SARS-CoV-2 virus and discusses the drugs that are currently in use to treat COVID-19.
It is well established that nesting materials are an important inclusion for mouse cages. We wanted to determine whether there was a significant difference in mice activity when offered three different material choices and whether there was any correlation between activity in the cage and nest complexity.
Dr. Thomas Scullion discusses how to leverage NHP exploratory toxicology studies to guide and explore lead optimization, dosing paradigms, and future GLP studies.
Experts discuss case studies and experimental data from various applications using a newly developed automated system to measure vision based on the optomotor reflex.
A growing body of evidence suggests that Home Cage Monitoring studies are becoming key tools for in vivo animal research for three main reasons: reduction in animal distress thereby increasing welfare, minimization of biases (wanted and unwanted), and increased reproducibility of data.
Experts discuss and demonstrate how to set up and plan experiments combining virtual reality (VR) with real-time eye tracking and physiology data measurement.
Tonya Coulthard discusses the SuperArgus PET/CT systems, reviewing both basic and unique imaging capabilities, including real-time imaging of awake animals as well as multiplexed PET imaging of standard and non-standard isotopes.
Experts discuss a radiopaque polymerizing contrast agent that can be used to overcome the inherent challenges in distinguishing soft tissues with micro CT.
Industry professionals define what it means to publish Open Access, the different types, factors that influence funding, and share how to manage related fees from grants and budgets in several examples.
Experts demonstrate how to set up an eye tracking experiment and combine this data with physiological data such as ECG, EEG, EDA, EMG/fEMG and RSP.
Leigh Goedeke, PhD reviews spontaneous nonhuman primate (NHP) models of NAFLD and metabolic syndrome as a more clinically-relevant preclinical study platform.
Experts discuss how to set up a remote eye tracking experiment, present stimuli, collect physiology data and analyze your results.
Dr. Kerry Hughes, of Almac, discusses the application of NMR in the GMP setting to ensure continued high-quality performance of drug discovery workflows.
Chris Rand discusses the updated 200A Olfactometer from Aurora Scientific. He walks through setting up the system before sharing best practices, all while demonstrating the integral functions of the system.
Experts discuss the A-to-Z of assessing muscle performance and contractile function in single muscle fibers.
Experts discuss the use of a novel movement responsive rodent caging system as a means to minimize animal stress and enable unique discovery in many research applications, namely neuroscience, animal behaviour, drug discovery and cardiometabolic disease.
Dr. Robert Gould and Mike Girand discuss methods and applications for the use of EEG as a highly translational biomarker for sleep, substance use disorder and CNS disorders.
Suzie Buono discusses the work she and her team have done to provide an example of treating a dominant disease by targeting both alleles, suggesting that this strategy may be applied to other dominant diseases.
The MRL/MpJ mouse strain has been touted as a "superhealer" although different tissues have previously displayed different levels of healing ability. We sought to test that ability in skeletal muscle.
Jordan Fuqua discusses how autophagy and proteolytic processes are regulated in skeletal muscle, specifically looking at ULK1 and ULK2 and their roles in maintaining skeletal muscle homeostasis, morphology, protein aggregate degradation and autophagy.
Matt Borkowski of Aurora Scientific discusses the latest software update for their Dynamic Muscle Control and Analysis Software, DMC LabBook.
Scientists present data on 2-photon imaging of hippocampal place cells and on stress monitoring in head-fixed awake behaving mice.
Experts discuss how opioids affect sleep and respiratory depression in preclinical mouse models.
Fred Beasley, PhD discusses how to select the most appropriate animal models for your preclinical obesity studies.
Join Dr. Melanie White for a discussion on basic isolated Langendorff heart principles, key experimental design considerations, core technology requirements and best practice tips to support consistency and validation of your research.
Scientists present case studies featuring single-cell electrophysiology and 2-photon microscopy in head-fixed, behaving mice.
An essential webinar for researchers interested in recording facial electromyography (fEMG) to measure muscle activity associated with smiling and frowning.
This webinar is essential for researchers interested in the use of continuous EEG telemetry for seizure assessment in rodent epilepsy models.
Andrew Puca, PhD discusses techniques for optimizing preclinical diabetes research in spontaneously diabetic NHPs, with a focus on stress free assessments of glucose measurement and response using continuous glucose monitoring and the banana tolerance test.
An essential webinar for scientists interested in functional Near-Infrared Optical Imaging (fNIR) technology and how they can use it for cognitive neuroscience research.
Ronglih Liao, Davor Pavlovic and Matthew Ackers-Johnson address the most popular questions related to cardiomyocyte isolation, purification, culture and analysis.
Join Frazer Findlay for an educational webinar on the measurement and analysis of event-related Electrodermal Activity (EDA)
An educational webinar providing an overview of the effects of oxygen concentration during in vitro cell culturing and how to accurately determine and regulate O2 levels during experiments.
A webinar series focused on advances in technology, experimental design and laboratory methods in preclinical cardiovascular research.
An educational webinar for researchers interested in laser confocal endomicroscopy, including fundamental theoretical and practical knowledge and a discussion on key capabilities and research applications of the technology.
An essential webinar for scientists interested in recording synchronized video with physiological measurements in human or animal research applications.
Join Dr. Tim Hacker for a discussion on experimental design, strategy, technology, common challenges and best-practices associated with planning long-term, chronic models of cardiovascular disease in rodents.
Ronglih Liao and Davor Pavlovic discuss techniques for isolating myocytes using both traditional and Langendorff-free methodologies, including key considerations, best practices and how to achieve and confirm optimal myocyte quality
Aaron Stupica and Keshari Thakali discuss techniques tissue bath myography and present a unique case study looking at the effect of maternal obesity on offspring perivascular adipose tissue and vascular function.
An exclusive webinar focused on best practices, technical considerations and expert advice to ensure quality data and research outcomes using ADInstruments PowerLab and LabChart.
Scientists present wireless glucose monitoring methodology, best practices, research findings, and discuss the power of continuous glucose profiles in obesity, diabetes and cardiovascular research.
Experts discuss a novel method of recording serial measurements of cardiac function in rodents using high-resolution ultrasound paired with implantable telemetry.
Experts present new, ground breaking research using the latest in fibre optic sensing technology to obtain dissolved oxygen and microvascular blood perfusion in models of Acute Kidney Injury (AKI).
Experts in preclinical and clinical ECG safety assessment discuss how advances in arrhythmia detection and concentration effects modelling improve study outcomes.
A comprehensive overview of technology and methods for recording and analyzing extracellular action potentials, local field potentials and EEG in a variety of research models.
Experts discuss novel cuff electrodes for in vivo peripheral nerve research, including the importance of electrode design, how to select the right cuff, implantation techniques and application results from nerve stimulation and blocking.
Scientists discuss technological advancements and present novel application of new head-mounted, wireless sensors for neural recording and stimulation in conscious non-human primates.
An essential webinar series reviewing various technologies used to study exercise physiology, sports science and biomechanics in human subjects.
Experts discuss new configurable wireless technologies for single unit electrophysiology recording in small and large animals, with a focus on applications, methodology, data outcomes, and the impact these devices will have in research involving untethered, naturally behaving subjects.
A presentation on key issues effecting the accuracy and reproducibility of measuring Oxygen Consumption, VO2, via indirect calorimetry utilizing Metabolic Carts, and best-practices for scientists to drive more consistent and precise measurements.
Peter Delaney reviews trends and technological advancements in the field of in vivo fluorescence imaging, with a focus on new applications and capabilities as realized by confocal fluorescence endomicroscopy and 3D automated optical sectioning.
Tom Smith presents the fundamentals of invasive blood pressure measurements for preclinical research, including technical considerations and best-practices that lead to accurate and consistent results.
Frazer Findlay and William McMullen discuss new technology and methods for measuring metabolic data from human research participants
Building on its popular Biomechanics 101 Introduction, Noraxon turns it attention to the fundamental pillar of biomechanics: electromyography, or EMG. This informative session covers signal origin, acquisition, processing and analysis for a comprehensive and practical understanding of EMG research and assessment.
Scientists discuss the value and utility of heart rate variability (HRV) as a preclinical tool for studying both cardiovascular, and non-cardiovascular related diseases in small and large animal models.
Scientists discuss how to integrate metabolic phenotyping with behavioral paradigms, the importance of temporal resolution, and how to avoid common pitfalls when executing behavioral and metabolic tests.
Learn about new technology and methodology for fast data acquisition and analysis of cardiomyocyte function, leading to better lab practices and data interpretation.
Scientists discuss technological advancements and present novel application of new head-mounted, wireless sensors for neural recording and stimulation in conscious, freely moving animals.
Experts present telemetry implant procedure for wireless recording of EEG in rodents and share novel case studies focused on studying neural recordings to investigate sleep, energy expenditure and Alzheimer's Disease.
A webinar for scientists interested in learning about a novel technology designed to overcome the challenges of large animal eye and eye-brain research
A special Question & Answers webinar for cardiovascular researchers interested in learning how to apply and master the use of noninvasive blood flow velocity measurements to study cardiovascular function in rodents.
Tahl Holtzman, PhD presents an in-depth tour of the latest neurotechnology for large-scale, high-resolution extracellular single unit recording combined with optogenetics in anaesthetized, head-fixed and freely behaving animals
Professor Vaughan Macefield discusses Microneurography technique and research trends for the study of nerve stimuli and associated responses in human subjects.
An essential webinar for all BCI researchers. Dr. Ujwal Chaudhary and Dr. Bettina Sorger will highlight their groundbreaking research in the field of fNIRS based BCI for communication with healthy subjects and patients in completely locked-in state.