Turning Innovative Features Into Practical Benefits Within the Buxco Nose-Only Rodent Inhalation System
UV Shemesh presents Buxco's nose-only rodent inhalation system, highlighting how it can improve research efficiency and offer valuable insights in respiratory studies.
Exploring Predictive Biomarkers and ERK1/2 Phosphorylation: A New Horizon in Forecasting Survival and Response to Immune Checkpoint Blockade in Glioblastoma Treatment
In this webinar, Victor Arrieta highlights the link between p-ERK activation and improved survival in rGBM patients using anti-PD-1 immunotherapy.
Indwelling Portal Vascular Access Ports: Application, Advantages, and Management
In this webinar, Melanie Graham, MPH, PhD will highlight the benefits and reliability of using vascular access ports (VAPs) in animal models.
Successful Modification of a Rodent Surgical Procedure and Device for Vascular Access in Minipigs (Vascular Access Button)
Adrian Zeltner discusses the innovative use of the Rat Vascular Access Button in Göttingen Minipigs to streamline blood sampling and infusion.
The Use of Vascular Access Buttons in Rabbits for PK/TK Studies
Jon Ehrmann presents the use of vascular access buttons in rabbits as a solution to challenges in venipuncture, enhancing blood collection, and intravenous administration for pharmacokinetic studies.
Evaluation of Novel Therapies Using Spontaneous Seizure Models
In this webinar, Dr. Cameron Metcalf covers the technical requirements and benefits of spontaneous seizure models, addressing the challenges and optimization of 24/7 video-EEG data collection for epilepsy therapy development.
#ExpertAnswers: Jack Vanden Heuvel on Nuclear Receptor Profiling
Dr. Jack Vanden Heuvel from Penn State University answers questions from a recent webinar discussing the use of cell-based reporter [...]
Tick Tock: The Growing Risk of Lyme Disease and Efforts to Develop a Vaccine
In this blog we discuss Lyme disease, including reasons for increased prevalence, causes and symptoms, and vaccine developments.
Evaluation of TruVivo, an All-Human Hepatocyte Model for Mechanistic DMPK Investigations
Join Diane Ramsden, PhD, and Lindsey Whaley, MS, for an inside look at TruVivo™, a novel all-human in vitro hepatocyte system developed by LifeNet Health LifeSciences.
Video Interview – ALZET Osmotic Pumps
Clarisa Peer discusses ALZET Osmotic Pumps, the gold standard for controlled, automatic dosing of compounds in various research areas, including neuroscience, cancer research, cardiovascular, endocrinology, pharmacology research, and more.
#ExpertAnswers: Sam Sternberg on Genome Engineering
Sam Sternberg discusses a novel CRISPR-Cas9 system using programmable, RNA-guided transposase and highlighting its implications for genome engineering in cell and gene therapies.
#ExpertAnswers: Frauke Greve and Anna Borgström on Hepatic Safety Using 3D Liver Spheroids
Frauke Greve and Anna Borgström from InSphero highlight the latest advancements in hepatic safety assessment using 3D liver spheroids.
Save Time and Money When Prioritizing Drug Candidates: Using Cell-Based Reporter Assays for Nuclear Receptor Profiling
Dr. Jack Vanden Heuvel discusses the use of cell-based reporter assays for nuclear receptor profiling to efficiently prioritize drug candidates and minimize off-target effects.
Targeting Proteomics to Decipher Biology for the Drug Development Pipeline
Dr. Jeffrey Silva explores the role of mass spectrometry-based proteomics on drug discovery, disease mechanisms, and biomarker identification.
Leveraging Programmable CRISPR-Associated Transposases for Next-Generation Genome Engineering
Dr. Sam Sternberg discusses a novel CRISPR-Cas9 system using programmable, RNA-guided transposase, and highlights its implications for kilobase-scale genome engineering in cell and gene therapies.
Cancer Immunotherapy: Viruses, Vaccines, and other Immuno-Oncology Treatments
In this blog post, current cancer immunotherapy treatments are discussed, as well as some future directions for this rapidly developing field.
The 3D DILI Model of Success – from Biological Relevance to Industry Application
Experts from InSphero answer questions about the application of their 3D human liver microtissues for drug induced liver injury (DILI) experiments.
Rethink Your Impurity Analysis Strategy
In this webinar, Dr. Ejvind Mørtz discusses the benefits and applications of mass spectrometry (MS)-based host cell protein (HCP) analysis and why HCP ELISAs are insufficient for documenting product-related impurities. Watch to learn where to apply the assay in a typical process and what you gain from deploying it to your workflow.
Essential Bruker NMR Trainings 2023
Join Bruker experts online for 1 hour every month in this essential training program designed for NMR Scientists.
The 3D DILI Model of Success – from Biological Relevance to Industry Application
Dr. Anna Borgström and Dr. Frauke Greve present the latest advancements in hepatic safety assessment using 3D liver spheroids.
#ExpertAnswers: Audrey Dubourg and Gareth Guenigault on the Organ-On-A-Chip Approach
Audrey Dubourg and Gareth Guenigault from CN Bio discuss the value that an organ-on-a-chip approach can bring to drug discovery and development workflows, and how the regulatory landscape is shifting to encourage their widespread adoption.
It’s Life, but Not As We Know It: How Predictive Human Organ Models Are Transforming and Reshaping the Efficiency of Drug Discovery
Experts answer questions about the application of organ-on-a-chip technology for preclinical drug discovery research.
Industry Insights with Crown Bioscience: Targeting T Cells Within the Cancer-Immunity Cycle
In this episode of Industry Insights, Saskia De Man, PhD, Marrit Putker, PhD, and Pirouz Daftarian, PhD, from Crown Bioscience discuss assays and methods for evaluating T cell therapeutics, including organoids, co-cultures, and high content imaging.
#ExpertAnswers: Ejvind Mørtz on Protein Analysis
Ejvind Mørtz discusses the benefits and applications of mass spectrometry (MS)-based host cell protein (HCP) analysis and why HCP ELISAs are insufficient for documenting product-related impurities.
APS Physiology in Disease Modeling and Drug Development Roundtable
Key opinion leaders in cardiovascular physiology and bioengineering discuss best practices and challenges when modeling cardiomyopathies and other cardiovascular diseases using stem cells, engineered tissues and other novel platforms.