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Science News, Content, and Resources2022-05-26T16:19:59-04:00

Science News, Content, and Resources

  • Ferret model of respiratory inflammation FI

Protocol Preview: a Ferret Model of Respiratory Inflammation

While rodents have long been used to model many human diseases, their anatomical, physiological, and immunological differences from humans cannot be ignored when modeling respiratory inflammation. Recently, Khoury et al. demonstrated how ferrets can be used to model inflammatory respiratory disease and injury, which we review in this blog post.

  • Beat Synchronization in Rats FI

Are They Born This Way? Beat Synchronization in Rats in Response to Lady Gaga, Mozart, and More

Recently, Ito et al. sought to understand beat synchronization in rats and how it compares to humans, which has not been reported to date. In this blog post, we review their findings and how they contribute to our understanding of cross-species beat synchronization.

  • GPR55 Atherosclerosis FI

Orphan Receptor GPR55: A New Therapeutic Target for Atherosclerosis?

Since the role of GPR55 in adaptive B cell response regulation has not yet been reported in the context of atherosclerosis, Guillamat-Prats et al. have investigated how GPR55 in B cells affects atherosclerosis development. In this blog post, we highlight the main findings from this study, which was published this month in Nature Cardiovascular Research.

Mitochondrial Adaptations and Homeostasis: Student Research from the MHRC

The Muscle Health Research Centre (MHRC) is one of Canada's leading innovators in muscle physiology research. In this blog post, we finish our series of interviews with student researchers at the MHRC and learn more about their research objectives, findings, and goals.

  • DNA vaccination type 1 diabetes FI

Is DNA Vaccination the Future of Type 1 Diabetes Prevention and Management?

Given the fact that type 1 diabetes can vary considerably between individuals, a precision medicine-based therapeutic approach could revolutionize clinical care. Earlier this year, Postigo-Fernandez et al. evaluated a precision medicine approach to DNA vaccination in a mouse model of type 1 diabetes, which we review in this blog post.

  • Industry Insights with Crown Bioscience: In Vitro Technologies for Studying the Cancer-Immunity Cycle

Industry Insights with Crown Bioscience: In Vitro Technologies for Studying the Cancer-Immunity Cycle

In this episode of Share Science, Rajendra Kumari, PhD, and Gera Goverse, PhD, from Crown Bioscience answer questions about in vivo, in vitro, and ex vivo technologies and methods that can be used for immuno-oncology research along each step of the cancer-immunity cycle.

Sugar, Spice, and a Troubling Vice: Cardiovascular and Cancer Risk with Artificial Sweeteners

Artificial sweeteners appear to be the perfect solution to many of the health problems associated with high sugar consumption, but two recent publications may change the public's opinion on these sugar substitutes.

  • Industry Insights with Chris Rand from Aurora Scientific

Industry Insights with Chris Rand from Aurora Scientific

This episode of Share Science features Chris Rand, MSc, sales and marketing manager at Aurora Scientific. In this interview, Chris shares Aurora Scientific’s history, their journey within the preclinical research world, and their advance into the neuroscience space.

  • MRHC Student Research Interviews ISC #2 FI

Mitochondrial Contributions to Muscle Weakness: Student Research from the MHRC

The Muscle Health Research Centre (MHRC) is one of Canada's leading innovators in muscle physiology research. In this blog post, we continue our series of interviews with student researchers at the MHRC and learn more about their research objectives, findings, and goals.

  • Long COVID brain fog FI

Clearing the Brain Fog: Long COVID and Cognitive Impairment

One common post-COVID symptom is brain fog or "COVID fog," which may affect up to 25% of recovered individuals. Given the global prevalence of SARS-CoV-2 and the detrimental impact of such cognitive impairment, the public health implications are considerable. Fernández-Castañeda et al. recently examined the underlying neurological changes associated with COVID fog, which we review in this blog post.

  • Dopamine-mediated fear response in the amygdala FI

Fright or Delight? Dopamine-Mediated Fear Response in the Amygdala

Since little is known about how dopamine affects aversive learning in humans, Frick et al. recently sought to describe the role of dopamine in fear memory formation within the human amygdala, which we review in this blog post.

  • MRHC Student Interviews

The Future of Muscle Physiology: Student Research at the MHRC

The Muscle Health Research Centre (MHRC) is home to many researchers who push the boundaries of muscle physiology. In this blog post, we summarize an interview with three students from the Muscle Health Research Centre (MHRC) at York University.

  • Talking Real Science with Brent Sinclair

Talking Real Science with Brent Sinclair

This episode of Share Science features Brent Sinclair, PhD, a biology professor at Western University who researches insect thermal biology and organizes career events for graduate students. In this interview, Brent shares why these opportunities are so important for students as they get close to finishing their degrees, as well as his career path and passions in and out of the lab.

Protocol Preview: Creating an Artificial Human Thymus in Mice

The majority of treatments for immunodeficiencies are temporary fixes, in part due to a lack of preclinical models that can accurately predict immune responses in humans. However, a novel model recently published in Nature Methods has potential to greatly improve future immune response studies, which we review in this blog post.

  • Investigating muscle weakness and fatigue with Christopher Perry and Arthur Cheng

Investigating Muscle Weakness and Fatigue with the MHRC

The Muscle Health Research Centre (MHRC) is home to many researchers who push the boundaries of muscle physiology. For this blog, we summarize interviews with two professors from the MHRC who investigate the mechanisms of muscle weakness and fatigue: Christopher Perry and Arthur Cheng.

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