Dr. Will Redfern of AstraZeneca and Dr. Sara Wells of MRC Harwell discuss 24/7 monitoring of group-housed rodents in their true IVC racked home cage environment for safety pharmacology and phenotyping applications.

Dr. Will Redfern of AstraZeneca and Dr. Sara Wells of MRC Harwell discuss 24/7 monitoring of group-housed rodents in their true IVC racked home cage environment for safety pharmacology and phenotyping applications.

Actual Analytics Ltd. and its development partners present an exclusive webinar describing the applications of a novel Home Cage Analysis system for tracking behavior in group housed rodents, with retained identity, in regular IVC racked home cages. Discussions describe the types of new insights that can be obtained from 24/7 monitoring of research animals including activity differences in single and group animals and body temperature profiles in response to drug treatment. Presenters show how they are using this system in various applications from safety pharmacology in rats through to phenotyping studies in mice.

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Presenters

Associate Director
CVS & CNS Translational Centre of Expertise
AstraZeneca

Director
Mary Lyon Centre
MRC Harwell

Dr Sara Wells is the Director of the Mary Lyon Centre at MRC Harwell Institute, in her role she oversees and coordinates mouse genetics projects and animal welfare. She first became interested in genetics at the age of 16 and went on to study Genetics at the University of Sheffield. In the 90s when transgenic technology really took off, she moved to the National Institute for Medical Research to study for a PhD using genetic engineering techniques in rodents. Following a post-doctoral research period at the University of Bristol, she moved to MRC Harwell in 2002. Sara is driven by the continually changing field of genetics, its advancements and challenges. In particular genome editing and its possibilities for improving pre-clinical models, automated phenotyping and how it is going to change how we characterise genetically altered animals. Sara is a member of various national groups and committees including the LASA council (Laboratory Animal Science Association) and the animal welfare and ethical review bodies for two other establishments (one academic, one pharmaceutical). Sara is keen to promote technological opportunities which promise to be able to reduce and refine the work undertaken in animal research.

Production Partner

Actual Analytics Ltd.

Actual Analytics offers cutting edge video analysis technology to analyze behaviour in pre-clinical scientific research and drug development laboratories.

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