Peripheral and Cerebral Vascular Responses Following High-Intensity Interval Exercise
Dr. Bert Bond and Max Weston will present an overview on their study investigating the effects high-intensity interval exercise has on cerebrovascular health.
Inherited Retinal Dystrophy: Chronic Proinflammatory Signaling Accelerates the Rate of Degeneration
T.J. Hollingsworth, PhD, discusses findings from a recent study examining the effects of chronic proinflammatory signaling in inherited retinal dystrophy (IRD).
#ExpertAnswers: Davide Boido and Antoine Bergel on Multimodal Neuroimaging
Davide Boido and Antoine Bergel discuss their work on how state-of-the-art multimodal neuroimaging can be coupled with functional ultrasound to study neurovascular coupling across vigilance states.
#ExpertAnswers: Jastyn Pöpplau and Marilena Hnida on Prefrontal Networks
Jastyn A. Pöpplau and Marilena Hnida discuss their research on prefrontal networks in developing head-fixed mice, and the role of these networks in cognition and models of neurodevelopmental diseases.
Towards Automated Spikesorting using Artificial Intelligence on a Cloud-Based Platform
In this webinar, Dr. Fan Wu and Lidor Spivak discuss the use of artificial intelligence to automate electrophysiological data analysis, including a new cloud-based software platform.
The Blues & the Browns: Links between Depression and Gut Microbiota
Recently, Radjabzadeh et al., identified 13 genera of gut microbiota that have been implicated with symptoms of depression.
Brain-Derived Tau in Blood: the Future of Alzheimer’s Disease Diagnosis?
Recently published in Brain, Gonzalez-Ortiz et al. report the design and development of a novel blood-based biomarker specific to brain-derived tau. In this blog post, we dive into the advantages of their novel immunoassay over those that are commercially available, as well as its future implications for Alzheimer’s disease diagnosis.
Multimodal Neuroimaging Using Functional Ultrasound (fUS)
Drs. Davide Boido and Antoine Bergel show how state-of-the-art multimodal neuroimaging can be coupled with functional ultrasound (fUS) to study neurovascular coupling across vigilance states.
Developing Prefrontal Circuits and Their Role in Health and Disease
In this webinar, Dr. Ileana Hanganu-Opatz, Dr. Jastyn A. Pöpplau, and Marilena Hnida discuss their research on prefrontal networks in developing head-fixed mice, and the role of these networks in cognition and models of neurodevelopmental diseases.
Developing Retinal Gene Therapy for Zellweger Spectrum Disorder (ZSD)
Catherine Argyriou, PhD, discusses peroxisome disease and the development of a retinal gene therapy for PEX1-mediated Zellweger Spectrum Disorder.
Real-time IntraVital Microscopy (IVM): In Vivo Cellular-level Imaging of Internal Organs in a Live Animal
Join Pilhan Kim, PhD for an in-depth discussion on the All-in-One intravital two-photon and confocal microscopy system.
#ExpertAnswers: Connar Westgate on Intracranial Pressure Measurements
Connar Westgate discusses his research involving intracranial pressure measurements and the importance of understanding this physiological parameter for maintaining normal central nervous system function.
Novel Targets for Alzheimer’s Disease Treatment: Medin and PLD3
Given that Alzheimer's disease is multifactorial and heterogenous, drug development progress is more likely to occur if multiple pathways are considered. Two recent Nature publications have potentially identified medin and PLD3 as new targets for Alzheimer’s disease treatment, which we summarize in this mini-review.
#ExpertAnswers: Dennis Turner on the Metabolics of Dementia
Dennis Turner delves into dementia syndrome, the metabolic changes that occur, and the importance of proper physiological monitoring of animal models.
Are They Born This Way? Beat Synchronization in Rats in Response to Lady Gaga, Mozart, and More
Recently, Ito et al. sought to understand beat synchronization in rats and how it compares to humans, which has not been reported to date. In this blog post, we review their findings and how they contribute to our understanding of cross-species beat synchronization.
#ExpertAnswers: Jason Rogers and Eliala Salvadori on Infant Emotional Communication
Jason Rogers and Eliala Salvadori answer questions from a recent webinar that discussed research involving infant emotional communication patterns and coded behaviors.
#ExpertAnswers: Adrián Rodríguez-Contreras and Barbara Lind on Neurovascular Coupling
Adrián Rodríguez-Contreras and Barbara Lind discuss their work on neurovascular coupling in awake head-fixed and anesthetized mice, with a focus on the effects of anesthetics.
Understanding Intracranial Pressure in Freely Moving Rats
Join Connar Westgate, PhD for a deep dive into intracranial pressure measurements and the importance of understanding this physiological parameter for maintaining normal CNS function.
Industry Insights with Chris Rand from Aurora Scientific
This episode of Share Science features Chris Rand, MSc, sales and marketing manager at Aurora Scientific. In this interview, Chris shares Aurora Scientific’s history, their journey within the preclinical research world, and their advance into the neuroscience space.
Industry Insights with Chris Rand from Aurora Scientific
Chris Rand delves into the start and evolution of Aurora Scientific, and their journey within the preclinical research world.
Clearing the Brain Fog: Long COVID and Cognitive Impairment
One common post-COVID symptom is brain fog or "COVID fog," which may affect up to 25% of recovered individuals. Given the global prevalence of SARS-CoV-2 and the detrimental impact of such cognitive impairment, the public health implications are considerable. Fernández-Castañeda et al. recently examined the underlying neurological changes associated with COVID fog, which we review in this blog post.
Functional Recovery of the Musculoskeletal System Following Injury – Leveraging the Large Animal Model
Watch Dr. Sarah Greising discuss the current pathophysiologic understanding of the skeletal muscle remaining following traumatic musculoskeletal injuries.
Fright or Delight? Dopamine-Mediated Fear Response in the Amygdala
Since little is known about how dopamine affects aversive learning in humans, Frick et al. recently sought to describe the role of dopamine in fear memory formation within the human amygdala, which we review in this blog post.
#ExpertAnswers: Aaron Phillips on Neural Hemodynamic Control
Aaron Phillips discusses questions from a recent webinar on his research involving neural hemodynamic control in pre-clinical and clinical models.
In Vivo Modeling of Immune-mediated Optic Neuropathies
Oliver W. Gramlich, PhD, provides an in-depth discussion about the pathobiology and visual phenotype of immune-mediated optic neuropathies.
