Lora Heisler, PhD discusses the unique brain circuits that are controllers of body weight, reviews how our genes impact our waistline and explains how obesity medications leverage basic neurobiology to reduce hunger and decrease body weight.
In many western countries, nearly a quarter of us meet the criteria for clinical obesity and more than half of us are overweight. This is a medical concern because obesity is a serious risk factor for many major chronic illnesses, such as heart disease, type 2 diabetes and cancer, and as a result, obesity is associated with reduced lifespan by almost a decade. The rapid escalation in the prevalence of obesity and the paucity of obesity medications underscores the necessity of an understanding of the basic neurobiology underlying body weight.
During this webinar, Professor Heisler will discuss brain circuits that are the main known controllers of body weight, such as those activated by the adipocyte hormone leptin. She will review how our genes impact our waistline and will discuss crucial genes such as those in the melanocortin system. Professor Heisler will discuss how obesity medications capitalize on this basic neurobiology to promote satiety, reduce hunger and decrease body weight.
Key Topics Include:
- Gut to brain communication
- Key brain chemicals mediating satiety
- Key brain chemicals controlling hunger
Chair in Human Nutrition
University of Aberdeen