Clambake: An Algorithm to Decode Energy Expenditure Data from Metabolic Cages
In this webinar, Dr. Jonathan Brestoff discusses his research on metabolism and a new method to quantify metabolic data known as Clambake.
More Than What You Eat: The Regulation of Metabolic Health and Aging by Diet Composition and Activity
Join Dudley Lamming, PhD to learn how the specific composition of dietary protein and exercise influence metabolic health and aging.
Exploring Estrogen’s Role in Metabolism and the Use of 13C-Labeled Nutrients for Advanced Animal Physiology and Nutrition Research
In this Q&A, Dr. Reilly Enos and Dr. Levin answer questions about their research focused on estrogen signaling in obesity and metabolism in insect models, respectively.
The Sweet Truth: Unwrapping the Science of Semaglutide
Semaglutide, also known as Ozempic and Wegovy, has become increasingly popular -- but why? Here we discuss the mechanism behind these drugs, how they've become so well known, and what current research says about their long-term effects.
Exploring Estrogen’s Role in Metabolism and the Use of 13C-Labeled Nutrients for Advanced Animal Physiology and Nutrition Research
Dr. Reilly Enos and Dr. Eran Levin discuss estrogen's metabolic impact and how isotopic labeling and 13C-labeled nutrients can be used for animal physiology and nutrition research.
From Trauma to Binge Eating: How Early Life Experiences Impact the Leptin System
Early life trauma (ELT) has been identified as a risk factor for binge eating and obesity in adult life, but the neural mechanisms behind this phenomena have yet to be determined. In this blog post we discuss a recent publication from Shin et al., which delineates the circuitry of this ELT-induced maladaptive eating.
#ExpertAnswers: Dudley Lamming on the Influence of Sex and Genetic Background on Diet
Dudley Lamming, PhD, explains that “We Are More Than What We Eat”; Sex and Genetic background are important factors in observing responses to diet in mice.
#ExpertAnswers: Jonathan Brestoff on Energy Expenditure
Jonathan Brestoff explains how energy expenditure can be better described thanks to a new bioinformatic algorithm known as Clambake.
We Are More Than What We Eat: Dietary Interventions Depend on Sex and Genetic Background
Dudley Lamming, PhD, explains how sex and strain type are highly important factors in observing responses to dietary interventions in mice.
Recent Advances in Anti-Obesity Pharmacological Research
A review of current obesity treatments and their limitations, the need for animal models in obesity research, and emerging anti-obesity medications including incretin-based therapies, mitochondrial uncouplers, and various phytochemicals.
#ExpertAnswers: Marc Reitman and Oksana Gavrilova on Thermal Physiology
Marc Reitman and Oksana Gavrilova discuss the effects of cold, hot, and near-thermoneutral environments on mouse energy expenditure, body temperature, and behavior.
Thermal Physiology: The Effects of Environmental Temperatures on Energy Expenditure in Mice
Marc Reitman, MD, PhD and Oksana Gavrilova, PhD answer questions from their recent webinar on thermal physiology, energy expenditure, and thermoneutrality in a mouse model.
Cutting Edge Conversations 2022
The Cutting Edge Conversations series offers a deep dive into specific research areas and focused insights regarding market-relevant processes from respected firms in the industry.
Thermal Physiology: The Effects of Environmental Temperatures on Energy Expenditure in Mice
Marc Reitman, MD, PhD and Oksana Gavrilova, PhD discuss thermal physiology, energy expenditure, and thermoneutrality in a mouse model.
#ExpertAnswers: Caroline Wuyts on Pregnancy and Glucose
Join Caroline Wuyts, from KU Leuven - VIB, as she answers questions from a recent webinar where she discusses her research on pregnancy and monitoring glucose availability throughout the reproductive timeline of a mouse model.
Continuous Glucose Monitoring and Glycemic Variability in Pregnancy
Join Caroline Wuyts, MSc for a deep dive into her research on pregnancy and monitoring glucose availability throughout the reproductive timeline of a mouse model.
#ExpertAnswers: Aileen King on Experimental Protocol
Dr. Aileen King discusses how even small changes to experimental protocol can substantially impact both welfare and data interpretation when studying blood glucose homeostasis in mice.
Sex, Drugs and Protocol: How Researcher Choices Impact Experimental Outcomes in Preclinical Diabetes Research
Aileen King presents data showing that small alterations to experimental protocol and choice of model can impact on both welfare and data interpretation when studying blood glucose homeostasis in mice.
Remodeling of Pancreatic Innervation in Diabetes
Read the Q&A Report: Experts discuss the use of whole-organ assessment for comprehensive examination of pancreatic innervation in diabetes.
#ExpertAnswers: Sarah Stanley & Alexandra Alvarsson on Pancreatic Innervation in Diabetes
Experts discuss the use of whole-organ imaging of the pancreas to reveal close interactions between nerves and islets and dynamic regulation of islet innervation in diabetes.
#ExpertAnswers: Christopher Axelrod & Sander Kooijman on Rodent Models of Pharmacotherapy and Chronotherapy
In this episode of Expert Answers, Christopher Axelrod and Dr. Sander Kooijman discuss their research into combatting obesity using various new therapies.
#ExpertAnswers: Michael Czech on CRISPR-Enhanced Adipocyte Browning
In this episode of Expert Answers, Dr. Michael Czech discusses a novel CRISPR-based cell therapy which enhances adipose tissue "browning" as a treatment for metabolic disease.