A Breath of Not-So-Fresh Air: the Combined Effects of Air and Noise Pollution
While air and noise pollution have been well documented independently, their combined effects are insufficiently discussed, until recently. In this blog post, we discuss a recent publication from Kuntic et al. on the combined and individual effects of these pollutants in mice.
Talking Real Science with Martin YoungDarius Soo Lum
Martin Young shares his career path, background, and the influence and guidance he has received from through generations of scientific mentorship.
Talking Real Science with Martin Young
This episode of Share Science features Dr. Martin Young, a professor of medicine at the University of Alabama at Birmingham. In this interview he shares his journey into cardiac metabolism and chronobiology as well as some notable mentors that helped him along the way.
The Blues & the Browns: Links between Depression and Gut Microbiota
Recently, Radjabzadeh et al., identified 13 genera of gut microbiota that have been implicated with symptoms of depression.
#ExpertAnswers: Dudley Lamming on the Influence of Sex and Genetic Background on DietDarius Soo Lum
Dudley Lamming, PhD, explains that “We Are More Than What We Eat”; Sex and Genetic background are important factors in observing responses to diet in mice.
A Novel Ingestible Biosensor for Intestinal Metabolite Monitoring
De la Paz et al. have developed an ingestible, self-powered, and wireless biosensing capsule that can hopefully be used for the noninvasive diagnosis of gastrointestinal disorders in the future. Recently published in Nature Communications, the authors demonstrated how its real-time performance in a porcine model, which we summarize in this post.
#ExpertAnswers: Dennis Turner on the Metabolics of DementiaDarius Soo Lum
Dennis Turner delves into dementia syndrome, the metabolic changes that occur, and the importance of proper physiological monitoring of animal models.
#ExpertAnswers: Jonathan Brestoff on Energy ExpenditureDarius Soo Lum
Jonathan Brestoff explains how energy expenditure can be better described thanks to a new bioinformatic algorithm known as Clambake.
Is DNA Vaccination the Future of Type 1 Diabetes Prevention and Management?
Given the fact that type 1 diabetes can vary considerably between individuals, a precision medicine-based therapeutic approach could revolutionize clinical care. Earlier this year, Postigo-Fernandez et al. evaluated a precision medicine approach to DNA vaccination in a mouse model of type 1 diabetes, which we review in this blog post.
Mitochondrial Contributions to Muscle Weakness: Student Research from the MHRC
The Muscle Health Research Centre (MHRC) is one of Canada's leading innovators in muscle physiology research. In this blog post, we continue our series of interviews with student researchers at the MHRC and learn more about their research objectives, findings, and goals.
We Are More Than What We Eat: Dietary Interventions Depend on Sex and Genetic Background
Dudley Lamming, PhD, explains how sex and strain type are highly important factors in observing responses to dietary interventions in mice.
Strategic Approaches to Age-Related Metabolic Insufficiency and Transition into Dementia Syndrome
In this webinar, Dr. Dennis Turner delves into dementia syndrome, the metabolic changes that occur, and the importance of proper physiological monitoring of animal models.
Clambake: Decoding Factors That Contribute to Energy Expenditure
Join Jonathan Brestoff, MD, PhD, MPH, for an exploration of how energy expenditure can be better described thanks to a new bioinformatic algorithm known as Clambake.
Does Diabetes Promote COVID-19, or Does COVID-19 Promote Diabetes?
During the COVID-19 pandemic, many of those living with diabetes were required to follow strict guidelines to protect themselves against infection as they were at high risk of morbidity and mortality. This blog takes a look at the links between angiotensin-converting enzyme 2 (ACE2) expression and diabetes, as well as incident diabetes and long COVID.
#ExpertAnswers: Junseok Son on Maternal Exercise and Neonatal Health in MiceDarius Soo Lum
Junseok Son discusses his maternal exercise protocol and its effects on neonatal metabolic health in mice.
Recent Advances in Anti-Obesity Pharmacological Research
A review of current obesity treatments and their limitations, the need for animal models in obesity research, and emerging anti-obesity medications including incretin-based therapies, mitochondrial uncouplers, and various phytochemicals.
Application of Treadmill Exercise Using Mice as a Model for Studying the Influence of Maternal Exercise on Offspring Metabolic Reprogramming
Join Dr. Junseok Son for a discussion on how a maternal exercise of mice protocol can aid in explorations of the beneficial effects of exercise on neonatal health.
#ExpertAnswers: Marc Reitman and Oksana Gavrilova on Thermal PhysiologyDarius Soo Lum
Marc Reitman and Oksana Gavrilova discuss the effects of cold, hot, and near-thermoneutral environments on mouse energy expenditure, body temperature, and behavior.
Cutting Edge Conversations 2022Darius Soo Lum
The Cutting Edge Conversations series offers a deep dive into specific research areas and focused insights regarding market-relevant processes from respected firms in the industry.
Fine Tuning Nutrient Intake Timing for Cardiac Health
Martin Young discusses 24-hr circadian rhythms that influence processes like metabolism that are critical to cardiovascular function.
Thermal Physiology: The Effects of Environmental Temperatures on Energy Expenditure in Mice
Marc Reitman, MD, PhD and Oksana Gavrilova, PhD discuss thermal physiology, energy expenditure, and thermoneutrality in a mouse model.
#ExpertAnswers: Dale Abel on Aging ScienceSarah McFarlane
Dale Abel answers questions from a recent webinar that focuses on the mechanisms underlying heart failure in aging and diabetes.
#ExpertAnswers: Caroline Wuyts on Pregnancy and GlucoseDarius Soo Lum
Join Caroline Wuyts, from KU Leuven - VIB, as she answers questions from a recent webinar where she discusses her research on pregnancy and monitoring glucose availability throughout the reproductive timeline of a mouse model.
#ExpertAnswers: Jonas Treebak and Alexander Bartelt on Metabolic AdaptationsSydney Otomancek
In this episode of #ExpertAnswers join Dr. Jonas Treebak and Dr. Alexander Bartelt as they answer questions from a recent [...]
Continuous Glucose Monitoring and Glycemic Variability in Pregnancy
Join Caroline Wuyts, MSc for a deep dive into her research on pregnancy and monitoring glucose availability throughout the reproductive timeline of a mouse model.