Join George Portugal, PhD for an overview of microelectrode array (MEA) technology used for cardiac research and some best practices for integrating this technique into your research.
Microelectrode array (MEA) technology is a valuable tool for research using stem cell derived or primary cardiomyocytes. Networks of extracellular recording electrodes can allow investigators to rapidly screen compounds, monitor for toxicological effects, and study changes in conduction velocity or arrhythmia. Furthermore, this technology can also be applied to study changes in organoid, cardiac slice, or whole heart applications.
In this presentation, George discusses some of the methodological challenges to consider when using MEA technology for cardiac research. The discussion includes best practices to use with MEA recording and provides examples of recordings using cell culture, slice, and whole heart. Together, these methods can optimize MEA recording and allow it to be easily integrated as a new technique in the lab.
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Resources
Presenters
Senior Applications Scientist
Harvard Bioscience, Inc.
George Portugal received his PhD in Behavioral Neuroscience at Temple University in 2010 and was a postdoctoral scientist in the laboratory of Dr. Moron-Concepcion at Columbia University from 2010-2013. Since 2013, he has worked with Multichannel Systems and HEKA Eletronik to assist clients with adding electrophysiological techniques to their labs.
Production Partner
Harvard Bioscience, Inc.
Harvard Bioscience is a global leader in the manufacturing and distribution of solutions to advance life science research. For over 110 years, we have served the changing needs of life scientists in over 100 countries. Our expanding portfolio of brands include instruments for organ and animal research, cell analysis, molecular biology, fluidics, and laboratory consumables.
Multi Channel Systems MCS GmbH
Multi Channel Systems focuses on the development of precise scientific measuring instrumentation in the field of Electrophysiology for research groups at universities and for the pharmaceutical industry. MCS provides solutions for extra-cellular recordings with microelectrode arrays in vitro and in vivo as well as for electrical stimulation.
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