In this webinar, Dr. Sven Schönecker and Sara Mirsadeghi, MSc, discuss 3D Mesh Microelectrode Arrays (MEA) including new developments and applications.
In today’s fast paced research environment, drug testing, regulatory requirements, and alternative methods are at the forefront of neuroscience research. In this webinar, Dr. Sven Schönecker discusses the latest in 3D Mesh MEA’s, its ability for a more true-to-life system for studying organoids, and the versatility of the well-established MEA2100 system from Multi Channel Systems (MCS), an affiliate of Harvard Bioscience (HB).
The main challenge in the brain organoid field is to monitor neural network formation within development and manipulate the synaptic plasticity of mature brain organoids. Indeed, this challenge hinders neuroscientists from achieving all aspects of human brain-on-chip. In this webinar, Sara talks about how growing brain organoids around the electrodes, using Mesh MEA, brings neuroscientists closer to the brain-on-chip inherence.
Key Topics Include:
- Why organoids? – Advancements and alternative models to support the 3R’s (replace, reduce, refine) of animal models
- How did we get here? – Understand the challenges of 2D electrodes and the introduction of the 3D Mesh MEA
- Benefits of the platform – Electrophysiology simplified…simple integration and flexibility using a universal, well-established platform
- It’s all possible – Cell culture, slices, organoids, implantation, and beyond
Presenters
Global Product Manager, Multielectrode Array
Marketing
Multi Channel Systems
Sven is a Sr. Application Scientist, the Application Team Leader for Cellular and Molecular Technologies in EIMEA, and is now the global Product Manager for Multielectrode Arrays (MEA) at Multi Channel Systems.
Ph.D. student/Research Assistant
Neuroscience, Developmental and Regenerative Biology (NDRB)
University of Texas at San Antonio (UTSA)
Sara studies the electrophysiological properties of different brain organoids, derived from healthy donors as well as patients with congenital epilepsy, employing standard MEAs, 3D-MEAs and newer Mesh-MEAs.
Production Partner
Multi Channel Systems MCS GmbH
Multi Channel Systems focuses on the development of precise scientific measuring instrumentation in the field of Electrophysiology for research groups at universities and for the pharmaceutical industry. MCS provides solutions for extra-cellular recordings with microelectrode arrays in vitro and in vivo as well as for electrical stimulation.
Harvard Bioscience, Inc.
Harvard Bioscience is a global leader in the manufacturing and distribution of solutions to advance life science research. For over 110 years, we have served the changing needs of life scientists in over 100 countries. Our expanding portfolio of brands include instruments for organ and animal research, cell analysis, molecular biology, fluidics, and laboratory consumables.
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