In this webinar, experts present a standardized stem cell line and its differentiation into neural cells for disease modeling and assay development.
Reproducible research with human induced pluripotent stem cells (iPSCs) depends on thoroughly characterized and quality-controlled cell lines. In this webinar, Dr. Andrew Gaffney and Dr. Erin Knock from STEMCELL Technologies describe the generation of a standardized induced pluripotent stem cell (iPSC) line. Developed with the upcoming ISSCR Standards Initiative characterization guidelines in mind, this highly characterized line is karyotypically stable, demonstrates trilineage differentiation potential, and expresses undifferentiated cell markers. Further, STEMCELL has developed a highly pure, ready-to-use neural progenitor cell product expressing PAX6 and SOX1 over multiple passages.
Dr. Knock shows how these multipotent cells are suitable for customized downstream differentiation to various CNS cell types, such as forebrain neurons, midbrain neurons, and astrocytes. These progenitor cells are the ideal controls for standardizing downstream differentiation protocols, modeling diseases, and assay development.
Key Topics Include:
- Discover how STEMCELL’s induced pluripotent stem cell lines are derived and characterized
- Learn how to differentiate induced pluripotent stem cell lines into all three germ layers
- Explore the features of STEMCELL’s neural progenitor cell product
- Differentiate neural progenitor cells into a variety of neural cell types, including neurons and glia
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Director, Stem Cell Manufacturing and Commercialization
Associate Director, Neural Biology
Research & Development