Neurophysiology: Exploring Basic Research and Clinical Consequences
Neurophysiology: Exploring Basic Research and Clinical Consequences - A webinar series covering fundamentals, late-breaking research, and novel discoveries in the field of neuroscience & related disease models.
Fully Characterized, Standardized Human Induced Pluripotent Stem Cell Line and Ready-to-Use, High-Quality Neural Progenitor Cells for Downstream Differentiation Applications
In this webinar, experts present a standardized human induced pluripotent stem cell line and its differentiation into neural cells for disease modeling and assay development.
Chronological Age vs Biological Age: Can Aging be Reversed?
What can biological age tell us about our health? Is it a fixed number, or can it be reduced? A recent study from Poganik et al. investigates the fluctuations in biological age in response to physiological stress.
Video Interview – ALZET Osmotic Pumps
Clarisa Peer discusses ALZET Osmotic Pumps, the gold standard for controlled, automatic dosing of compounds in various research areas, including neuroscience, cancer research, cardiovascular, endocrinology, pharmacology research, and more.
Fast-Forward Your Custom Antibody Generation With Four Bio-Rad Services
Discover how Bio-Rad's bioanalytical services and SpyTag-SpyCatcher technology can speed up custom antibody generation and improve assay flexibility for challenging targets.
CBD’s Potential as an Anti-Cancer Agent
Chemotherapy treatment is incredibly difficult on patient wellbeing, but an unlikely plant-derived substance may yet improve the adverse side effects. In this blog, we discuss the use of CBD as a treatment for side effects like organ damage and drug resistance in cancer patients receiving chemotherapy.
#ExpertAnswers: Nataliia Beztsinna and Marten Hornsveld on Pre-Clinical Immuno-Oncology
Nataliia Beztsinna and Marten Hornsveld describe how the tumor microenvironment modulates clinical responses and how patient-derived ex vivo and engineered in vitro models can be used for pre-clinical immuno-oncology testing.
#ExpertAnswers: Frauke Greve and Anna Borgström on Hepatic Safety Using 3D Liver Spheroids
Frauke Greve and Anna Borgström from InSphero highlight the latest advancements in hepatic safety assessment using 3D liver spheroids.
Can the Immune System Protect after Repeated Myocardial Injury?
While the immune response to a single cardiac event has been well researched, few have reported on whether an adaptive immunity is observed after repeated cardiac injury. Here, we discuss a recent publication from Tiwary et al., in which they investigate the cytoprotective response after multiple cardiomyopathic injuries.
Save Time and Money When Prioritizing Drug Candidates: Using Cell-Based Reporter Assays for Nuclear Receptor Profiling
Dr. Jack Vanden Heuvel discusses the use of cell-based reporter assays for nuclear receptor profiling to efficiently prioritize drug candidates and minimize off-target effects.
How to Create CRISPR-Edited T Cells More Efficiently for Tomorrow’s Cell Therapies
Steven Loo-Yong-Kee presents Artisan Bio's STAR-CRISPR system for optimized gene editing in cell therapy, with a focus on the genetifc modification of T cells for cancer immunotherapy.
Targeting Proteomics to Decipher Biology for the Drug Development Pipeline
Dr. Jeffrey Silva explores the role of mass spectrometry-based proteomics on drug discovery, disease mechanisms, and biomarker identification.
What’s Next in Preclinical Cancer Immunotherapy Research?
Experts answers questions about key topics in the field of cancer immunotherapy, including new and emerging methods and future directions.
The 3D DILI Model of Success – from Biological Relevance to Industry Application
Experts from InSphero answer questions about the application of their 3D human liver microtissues for drug induced liver injury (DILI) experiments.
Rethink Your Impurity Analysis Strategy
In this webinar, Dr. Ejvind Mørtz discusses the benefits and applications of mass spectrometry (MS)-based host cell protein (HCP) analysis and why HCP ELISAs are insufficient for documenting product-related impurities. Watch to learn where to apply the assay in a typical process and what you gain from deploying it to your workflow.
The 3D DILI Model of Success – from Biological Relevance to Industry Application
Dr. Anna Borgström and Dr. Frauke Greve present the latest advancements in hepatic safety assessment using 3D liver spheroids.
#ExpertAnswers: Audrey Dubourg and Gareth Guenigault on the Organ-On-A-Chip Approach
Audrey Dubourg and Gareth Guenigault from CN Bio discuss the value that an organ-on-a-chip approach can bring to drug discovery and development workflows, and how the regulatory landscape is shifting to encourage their widespread adoption.
It’s Life, but Not As We Know It: How Predictive Human Organ Models Are Transforming and Reshaping the Efficiency of Drug Discovery
Experts answer questions about the application of organ-on-a-chip technology for preclinical drug discovery research.
Novel Targets for Alzheimer’s Disease Treatment: Medin and PLD3
Given that Alzheimer's disease is multifactorial and heterogenous, drug development progress is more likely to occur if multiple pathways are considered. Two recent Nature publications have potentially identified medin and PLD3 as new targets for Alzheimer’s disease treatment, which we summarize in this mini-review.
APS Physiology in Disease Modeling and Drug Development Roundtable
Key opinion leaders in cardiovascular physiology and bioengineering discuss best practices and challenges when modeling cardiomyopathies and other cardiovascular diseases using stem cells, engineered tissues and other novel platforms.
It’s Life, but Not As We Know It: How Predictive Human Organ Models Are Transforming and Reshaping the Efficiency of Drug Discovery
Dr. Audrey Dubourg and Dr. Gareth Guenigault explore the value that an organ-on-a-chip approach can bring to drug discovery and development workflows, and how the regulatory landscape is shifting to encourage their widespread adoption.
Rethink your Impurity Analysis Strategy
In this webinar, Dr. Ejvind Mørtz discusses the benefits and applications of mass spectrometry (MS)-based host cell protein (HCP) analysis and why HCP ELISAs are insufficient for documenting product-related impurities. Watch to learn where to apply the assay in a typical process and what you gain from deploying it to your workflow.
Analyzing the Suppressive TME in in Vitro Based Assays
Experts describe suppressive tumor immune microenvironment compartments and patient-derived tissue technologies capable of recapitulating the TME for clinically-relevant studies.
What’s Next in Preclinical Cancer Immunotherapy Research?
This webinar will include a panel discussion of key topics in the field of cancer immunotherapy, including new and emerging methods, recent publications, and future directions.
Targeting T Cells Within the Cancer Immunity Cycle
In this webinar, speakers will discuss the role of T cell biology in cancer immunotherapy.
