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Drug Discovery & Development

Drug Discovery & Development

  • Preclinical Animal Models of IBD, GVHD, and Pulmonary Disease

Preclinical Animal Models of IBD, GVHD, and Pulmonary Disease

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Join BioModels’ Scientists, Andrew Borkowski, PhD and Nicole Smith, PhD, as they discuss a selection of key preclinical models of inflammatory disease, including models of Inflammatory Bowel Disease (IBD)/colitis, Graft vs Host Disease (GvHD), and pulmonary disease, focusing on the utility of clinically relevant endpoints that create highly translational models of human disease.

Assessing Antigen-Specific T Cell Functionality With Dendritic Cell/CD8⁺ T Cell Co-Culture

On December 12, 2023, STEMCELL Technologies' Dr. Catherine Ewen described, in detail, how to set up DC (dendritic cell) and CD8ᐩ T cell co-culture experiments that generate antigen-specific CD8ᐩ T cells, and how to assess CD8ᐩ T cell proliferation, functionality, and killing activity. In this Q&A report, you can read her answers to questions asked by the audience. Answers have been edited for length and/or clarity.

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