Dr. Matt Silva showcases the power of cryo-fluorescence tomography (CFT) in advancing immunotherapy research.

Cell-based immunotherapy is an emerging development in personalized cancer treatment where one application includes utilizing engineered immune cells that target cancer cells and engage the immune system to eradicate the disease. During preclinical development of these immunotherapies, it is essential to visualize cell distribution to both target and non-target tissues as well as gain critical information on immune engagement.

In this webinar, Dr. Matt Silva, CEO of Emit Imaging shows how whole-body cryo-fluorescence tomography (CFT) imaging will revolutionize cell and immunotherapy research. CFT enables multiplexing of cell tracking and localization with target and non-target tissue with immune activation via constitutive or imaging probe fluorescence. He covers the fundamentals of CFT imaging via the Emit XerraTM system and reviews examples of recent work on the platform.

Key Topics Include:

  • Introduction to Cryo-Fluorescence Tomography (CFT) for immunotherapy research
  • Overview of capabilities of the Emit Xerra system
  • Real-world examples and applications of CFT for cancer research

Resources

Presenters

Matthew Silva, ;PhD

Matthew Silva, PhD

CEO
EMIT Imaging

Matthew Silva, PhD, is the CEO of Emit Imaging, the leader in Cryo-Fluorescence Tomography (CFT) imaging. Previously, he served as CEO of Invicro, a global imaging CRO and led the strategic vision and mission to support the drug discovery and development community with diverse imaging services spanning preclinical and clinical applications. Prior to Invicro, he led imaging biomarker groups at Vertex, Amgen, Millennium and Takeda Pharmaceuticals. Matt holds a Ph.D. in Biomedical Engineering from Worcester Polytechnic Institute.
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Production Partner

EMIT Imaging

EMIT Imaging is at the forefront of Cryo-Fluorescence Tomography (CFT) technology, an advanced ex vivo molecular imaging technique that offers high-resolution visualization of drug distribution and protein expression. Their flagship system Xerra provides a detailed 3D data set combining high-sensitivity fluorescence imaging with anatomical imaging, with applications including drug pharmacokinetics/pharmacodynamics, phenotyping and model development, biodistribution, gene/protein expression, and cell tracking.

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EMIT Imaging

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