retinopathy Archives

Developing a Novel Gene Therapy for Kcnv2 Retinopathy

Sydney Otomancek2024-01-25T17:01:44-05:00Genetics & Genomics, Vision Research|

Livia Carvalho, PhD discusses her team's successful development of a novel AAV-based gene therapy approach for KCNV2 retinopathy in a Kv8.2 knockout mouse model.

Assessing Neuroinflammation-Related Neural Damage by Monitoring the Retinotectal System

hayleighisc2021-08-17T16:24:51-04:00Neuroscience, Vision Research|

Dr. Janos Groh discusses how neuroinflammation amplifies neural damage and disease outcome in models of various disorders, and the value of monitoring the retinotectal system to assess neural disease progression and associated treatment efficacy.

The Role of Nogo-A in Visual Deficits Induced by Retinal Injury

hayleighisc2021-08-17T16:23:35-04:00Neuroscience, Vision Research|

Julius Baya Mdzomba, PhD shows the link between Nogo-A, a membrane protein and potent inhibitor of neuronal growth, and visual deficits aggravation after retinal injury.

Visual Acuity as a Relevant Phenotype in Mouse Models of Rare Disease

hayleighisc2021-08-17T16:10:55-04:00Neuroscience, Vision Research|

Zoë Bichler, PhD and Maximiliano Presa, PhD present various projects where visual acuity measurements have been valuable for characterizing progression in rare diseases.