Chronological Age vs Biological Age: Can Aging be Reversed?
What can biological age tell us about our health? Is it a fixed number, or can it be reduced? A recent study from Poganik et al. investigates the fluctuations in biological age in response to physiological stress.
#ExpertAnswers: Sam Sternberg on Genome Engineering
Sam Sternberg discusses a novel CRISPR-Cas9 system using programmable, RNA-guided transposase and highlighting its implications for genome engineering in cell and gene therapies.
Save Time and Money When Prioritizing Drug Candidates: Using Cell-Based Reporter Assays for Nuclear Receptor Profiling
Dr. Jack Vanden Heuvel discusses the use of cell-based reporter assays for nuclear receptor profiling to efficiently prioritize drug candidates and minimize off-target effects.
Leveraging Programmable CRISPR-Associated Transposases for Next-Generation Genome Engineering
Dr. Sam Sternberg discusses a novel CRISPR-Cas9 system using programmable, RNA-guided transposase, and highlights its implications for kilobase-scale genome engineering in cell and gene therapies.
Developing Retinal Gene Therapy for Zellweger Spectrum Disorder (ZSD)
Catherine Argyriou, PhD, discusses peroxisome disease and the development of a retinal gene therapy for PEX1-mediated Zellweger Spectrum Disorder.
Cardiovascular Regenerative Medicine: Deconstructing Regenerative Therapeutics
Eduardo Marbán, MD, PhD, answers the top questions from his webinar on the complexities of regenerative cardiovascular medicine and the future directions for cell therapies.
Optimizing CD34+ Cell Genome Editing for Efficiency and HSPC Maintenance
Experts answer questions about CD34+ cell gene editing, methods to evaluate genome editing efficiency, and optimal culture conditions to maintain HSPC function and long-term editing effects.
Creating Better Gene-Edited Cell Lines with the FAST-HDR System
Dr. Oscar Perez and Dr. Jon Weidanz discuss the basis of the FAST-HDR gene-editing system and present case studies highlighting several applications.
Integration of the HTG Transcriptome Panel into Preclinical and Clinical Programs to Drive Precision Medicine Research
Dr. Peter Ansell discusses the use of novel RNA-based gene expression profiling methods for clinical and preclinical oncology research.
Applications of Single-Cell Sequencing: Innovative and Tailor-Made Services
Join Bastiaan Bijl, MSc, and Dylan Mooijman, PhD, as they provide an introduction to single-cell sequencing and its potential applications with user cases.
Cardiovascular Regenerative Medicine: Deconstructing Regenerative Therapeutics
Watch Eduardo Marbán, MD, PhD give a deep dive into the complexities of regenerative cardiovascular medicine and the future direction for cell therapies.
Optimizing CD34+ Cell Genome Editing for Efficiency and HSPC Maintenance
Experts provide tips and tricks to lock down effective genome editing conditions for CD34+ cells, methods to evaluate genome editing efficiency, and optimal culture conditions to maintain HSPC function and long-term editing effects.
The Variant-Rich Biobank: An Insider’s Look
Experts provide a showcase of Precision for Medicine's variant-rich biobank. including discussion on biospecimen types, applications, screening methods, and support for companion diagnostic development.
Spectronaut: Expand Biological Insights with DIA Proteomics
Oliver Bernhardt and Andreas-David Brunner answer questions about Spectronaut 15 with a specific focus on directDIA usage in proteomics.
Spectronaut: Expand Biological Insights with DIA Proteomics
Data-independent acquisition (DIA) has become the method of choice for large-scale discovery proteomics. Its application for single-cell analysis promises to be more sensitive, robust, and reproducible than other proteomic approaches but is still a fairly unexplored territory.
