Alexandra Lubin

Alexandra Lubin, PhD

Post-Doctoral Research Associate

UCL Cancer Institute

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Dr. Lubin studied Natural Sciences at Jesus College at the University of Cambridge, specialising in Chemistry and graduating with a masters in 2014. From there Dr. Lubin moved to Imperial College London where she completed her PhD in Chemical Biology ‘Epigenetic therapeutics in malaria – a chemical biological approach towards the validation of histone lysine methyltransferase inhibition in P. falciparum.’ Dr. Lubin then joined the Laboratory of Prof. Elspeth Payne in the Cancer Institute at University College London as a post-doc in 2018. Using zebrafish as a model organism, they try to understand the mechanisms of myelodysplastic syndrome (MDS) and acute myeloid leukaemia (AML), with the aim of developing novel therapeutic avenues for these diseases. Her main project involves developing a high-throughput automated drug screen in live zebrafish embryos, to screen for novel compounds that are synthetic lethal to haematopoietic stem cells that carry mutations that are common in MDS and AML, in particular Dnmt3a.